Naturally occurring antioxidant therapy in Alzheimer's disease

AE Collins, TM Saleh, BE Kalisch - Antioxidants, 2022 - mdpi.com
It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …

Blood-based biomarkers for Alzheimer's disease diagnosis and progression: an overview

A Varesi, A Carrara, VG Pires, V Floris, E Pierella… - Cells, 2022 - mdpi.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disease characterized by
amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain …

Treatment of Alzheimer's disease: beyond symptomatic therapies

FR Buccellato, M D'Anca, GM Tartaglia… - International Journal of …, 2023 - mdpi.com
In an ever-increasing aged world, Alzheimer's disease (AD) represents the first cause of
dementia and one of the first chronic diseases in elderly people. With 55 million people …

Oxytosis/ferroptosis in neurodegeneration: the underlying role of master regulator glutathione peroxidase 4 (GPX4)

NJ Dar, U John, N Bano, S Khan, SA Bhat - Molecular neurobiology, 2024 - Springer
Oxytosis/ferroptosis is an iron-dependent oxidative form of cell death triggered by lethal
accumulation of phospholipid hydroperoxides (PLOOHs) in membranes. Failure of the …

Intracellular molecular targets and signaling pathways involved in antioxidative and neuroprotective effects of cannabinoids in neurodegenerative conditions

A Tadijan, I Vlašić, J Vlainić, D Đikić, N Oršolić… - Antioxidants, 2022 - mdpi.com
In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic
cannabinoids have received growing interest as treatment options in neurodegenerative …

Single-atom transition metals (Rh, Ir, Co) doped silicon carbide nanotubes (SiCNT) as nonenzymatic nitrotyrosine (NTS) sensor: Insight from theoretical calculations

GA Okon, FO Ogungbemiro, H Louis, I Benjamin… - Computational and …, 2023 - Elsevier
Abstract Transition metals Namely Rhodium (Rh), Iridium (Ir), and Cobalt (Co) doped silicon
carbide nanotube (SiCNT) surfaces were theoretically investigated using first-principles …

Circular RNAs: emblematic players of neurogenesis and neurodegeneration

M D'Anca, FR Buccellato, C Fenoglio… - International journal of …, 2022 - mdpi.com
In the fascinating landscape of non-coding RNAs (ncRNAs), circular RNAs (circRNAs) are
peeping out as a new promising and appreciated class of molecules with great potential as …

Marine sources of DHA-rich phospholipids with anti-Alzheimer effect

I Ferreira, AP Rauter, NM Bandarra - Marine Drugs, 2022 - mdpi.com
Alzheimer's disease (AD) is a complex and progressive disease, which affects millions of
people around the world. Despite the many efforts over the years to find efficient …

Physical activity vs. redox balance in the brain: brain health, aging and diseases

P Sutkowy, A Woźniak, C Mila-Kierzenkowska… - Antioxidants, 2021 - mdpi.com
It has been proven that physical exercise improves cognitive function and memory, has an
analgesic and antidepressant effect, and delays the aging of the brain and the development …

Microbiota dysbiosis caused by dietetic patterns as a promoter of Alzheimer's disease through metabolic syndrome mechanisms

V Navalón-Monllor, L Soriano-Romaní, M Silva… - Food & Function, 2023 - pubs.rsc.org
Microbiota dysbiosis and metabolic syndrome, consequences of a non-adequate diet,
generate a feedback pathogenic state implicated in Alzheimer's disease development. The …