Serotonin is a naturally occurring vasoactive substance that has diverse cardio-
physiological effects. These effects can be explained by the existence of serotonin receptor …

Cardiovascular diseases and depression are significant health burdens and increasing
evidence suggests a causal relationship between them. The incidence of depression among …

Serotonin, or 5‐hydroxytryptamine, is a naturally‐occurring vasoactive substance found
primarily in the brain, enterochromaffin tissue, and blood platelets. It has diffuse …

We previously demonstrated a change in the receptors mediating 5-hydroxytryptamine (5-
HT)-induced contraction in arteries of deoxycorticosterone acetate (DOCA)-salt-hypertensive …

Arterial hyperresponsiveness to serotonin (5-hydroxytryptamine, 5-HT) is observed in
experimental models and human forms of hypertension. Presently, we test the hypothesis …

Large arteries from hypertensive subjects are hyperresponsiveness to 5-hydroxytryptamine
(5-HT). We tested the hypothesis that small arteries (225 μ ID) have a profile similar to …

We studied the acute effects of ketanserin, a serotonin S 2 antagonist, on systemic and
splanchnic hemodynamics in 11 patients with cirrhosis. Mean arterial pressure decreased …

Study objective–The aim was to investigate further the endothelium dependent vasodilator
action of 5-hydroxytryptamine (5-HT) on the rat coronary circulation. Design–Using saponin …

A 60-year-old man, known for stable coronary artery disease, was admitted for suspected
unstable angina. In the previous month, the patient presented with progressive dyspnea on …

Crk-associated substrate (CAS), a 130-kDa adaptor protein, was discovered as a tyrosine
kinase substrate of Src that was important to cellular motility and actin filament formation. As …