[HTML][HTML] Voluntary wheel running: patterns and physiological effects in mice

G Manzanares, G Brito-da-Silva… - Brazilian journal of …, 2019 - SciELO Brasil
Exercise can prevent and improve the pathophysiology of diseases and promote healthy
aging. Thus, understanding the mechanisms that regulate the beneficial effects of exercise …

Guidelines for animal exercise and training protocols for cardiovascular studies

DC Poole, SW Copp, TD Colburn… - American Journal …, 2020 - journals.physiology.org
Whole body exercise tolerance is the consummate example of integrative physiological
function among the metabolic, neuromuscular, cardiovascular, and respiratory systems …

Phosphoinositide 3-kinase (p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

JR McMullen, T Shioi, L Zhang… - Proceedings of the …, 2003 - National Acad Sciences
An unresolved question in cardiac biology is whether distinct signaling pathways are
responsible for the development of pathological and physiological cardiac hypertrophy in …

Intensity-controlled treadmill running in mice: cardiac and skeletal muscle hypertrophy

OJ Kemi, JP Loennechen, U Wisløff… - Journal of applied …, 2002 - journals.physiology.org
Whereas novel pathways of pathological heart enlargement have been unveiled by thoracic
aorta constriction in genetically modified mice, the molecular mechanisms of adaptive …

[HTML][HTML] Metabolic syndrome and urologic diseases

I Gorbachinsky, H Akpinar, DG Assimos - Reviews in urology, 2010 - ncbi.nlm.nih.gov
Metabolic syndrome (MetS) is a complex entity consisting of multiple interrelated factors
including insulin resistance, central adiposity, dyslipidemia, endothelial dysfunction and …

[HTML][HTML] Animal exercise studies in cardiovascular research: Current knowledge and optimal design—A position paper of the Committee on Cardiac Rehabilitation …

Y Bei, L Wang, R Ding, L Che, Z Fan, W Gao… - Journal of Sport and …, 2021 - Elsevier
Growing evidence has demonstrated exercise as an effective way to promote cardiovascular
health and protect against cardiovascular diseases However, the underlying mechanisms of …

Schisandrin B attenuates airway inflammation and airway remodeling in asthma by inhibiting NLRP3 inflammasome activation and reducing pyroptosis

X Chen, Z Xiao, Z Jiang, Y Jiang, W Li, M Wang - Inflammation, 2021 - Springer
Asthma is a chronic inflammatory disorder of the airways. Schisandrin B (SB) is the main
effective component. This study investigated the effects of SB on airway inflammation and …

The adaptive potential of skeletal muscle fibers

D Pette - Canadian Journal of Applied Physiology, 2002 - cdnsciencepub.com
Les cellules des muscles squelettiques des mammifères ont un grand potentiel d'adaptation.
Ce potentiel d'adaptation découle de la capacité d'ajustement des fibres musculaires à des …

Fatty acids identified in the Burmese python promote beneficial cardiac growth

CA Riquelme, JA Magida, BC Harrison, CE Wall… - Science, 2011 - science.org
Burmese pythons display a marked increase in heart mass after a large meal. We
investigated the molecular mechanisms of this physiological heart growth with the goal of …

Creb coactivators direct anabolic responses and enhance performance of skeletal muscle

NE Bruno, KA Kelly, R Hawkins… - The EMBO …, 2014 - embopress.org
During the stress response to intense exercise, the sympathetic nervous system (SNS)
induces rapid catabolism of energy reserves through the release of catecholamines and …