The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to
what was generally believed, it is now clear that distinct cell types expressing unique …

Allosteric receptor modulation is an attractive concept in drug targeting because it offers
important potential advantages over conventional orthosteric agonism or antagonism …

One plausible explanation for the controversy that surrounds the causes and clinical
management of obesity is the notion that overeating and obesity may only be a couple of …

A cDNA clone encoding a novel member of the putative taste receptor T1R family,
designated T1R3, was isolated from circumvallate papillae of the mouse tongue using …

Bitter taste perception is a conserved chemical sense against the ingestion of poisonous
substances in mammals. A multigene family of G-protein-coupled receptors, T2R (so-called …

Soy proteins are very important protein source for human being and livestock. Enzymatic
hydrolysis of soy protein can enhance or reduce its functional properties and improve its …

Background Taste receptor cells are responsible for transducing chemical stimuli into
electrical signals that lead to the sense of taste. An important second messenger in taste …

Sweetness is the preferred taste of humans and many animals, likely because sugars are a
primary source of energy. In many mammals, sweet compounds are sensed in the tongue by …

G protein-coupled receptors (GPCRs) represent the largest family of transmembrane
receptors and are prime therapeutic targets. The odorant and taste receptors account for …

The anatomy, physiology and psychology of taste provide a glimpse into a uniquely
heterogeneous sensory world; a world that is robust in its importance to flavor, redundant in …