To clarify the regional differences in the expression and functional significance of Gα-
gustducin in soft palate (SP) and fungiform (FF) taste buds, we examined the coexpression …

The five basic taste modalities, sweet, bitter, umami, salty and sour induce changes of Ca2+
levels, pH and/or membrane potential in taste cells of the tongue and/or in neurons that …

L-Glutamate and 5-ribonucleotides are known to elicit a unique taste,“umami,” that is distinct
from the tastes of sweet, salt, sour and bitter. Recent progress in molecular biology has …

Glutamate is one candidate for the neurotransmitters and/or neuromodulators involved in
taste signaling in taste buds. Group II metabotropic glutamate receptors (mGluRs: mGluR2 …

The sense of taste enables vertebrates in their natural ecosystem to select suitable foods
and to consume species‐appropriate diets. To this end the oral taste receptors serve the …

In vertebrates, the taste system provides information used in the regulation of food ingestion.
In mammals, each cell group within the taste buds expresses either the T1R or the T2R taste …

Taste bud cells (TBCs) express various neurotransmitter receptors assumed to facilitate or
modify taste information processing within taste buds. We investigated the functional …

Tastant detection in the oral cavity involves selective receptors localized at the apical
extremity of a subset of specialized taste bud cells called taste receptor cells (TRCs). The …

The taste buds are composed of heterogeneous cell populations with diverse properties and
at different stages of maturity. It is important to define the relationships between cell …

The mammalian tastes of sweet, umami, and bitter are initiated by activation of G protein-
coupled receptors (GPCRs) of the T1R and T2R families on taste receptor cells. GPCRs …