Combinations of RAD51 and PARP inhibitors

AC Castro, M Day, T Maclay, CC McComas… - US Patent …, 2023 - Google Patents
2021-06-08 Assigned to CYTEIR THERAPEUTICS, INC. reassignment CYTEIR
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Aminopyrimidines as SYK Inhibitors

MD Altman, BM Andresen, KL Arrington… - US Patent App. 14 …, 2014 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
43502894&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors

TA Miller, A Petrocchi, ET Romeo, D Vitharana… - US Patent …, 2017 - Google Patents
US9670196B2 - Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase
inhibitors - Google Patents US9670196B2 - Thiazole-substituted aminoheteroaryls as …

Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors

NJ Anthony, BM Andresen, AB Northrup… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amino heteroaryl compounds of the
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein X, X2, X3, X4, Y', Y?, Y> …

Heterocyclic compounds and uses thereof

AC Castro, CA Evans, S Janardanannair… - 2015 - Google Patents
WO2015051244A1 - Heterocyclic compounds and uses thereof - Google Patents
WO2015051244A1 - Heterocyclic compounds and uses thereof - Google Patents …

Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors

MD Altman, BM Andresen, KL Arrington… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amin opyridine compounds of the
Formula (I)(I) or pharmaceu tically acceptable salts thereof, wherein RRRRR RC, and the …

Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders

JL Kutok, DG Winkler, VJ Palombella - 2022 - Google Patents
A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, eg
guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring …

Amino-pyridine-containing spleen tyrosine kinase (syk) inhibitors

ET Romeo, MR Machacek, BW Trotter, TA Miller… - 2012 - Google Patents
WO2012151137A1 - Amino-pyridine-containing spleen tyrosine kinase (syk) inhibitors - Google
Patents WO2012151137A1 - Amino-pyridine-containing spleen tyrosine kinase (syk) inhibitors …

Combination therapies

JL Kutok - 2017 - Google Patents
DEVSOMFAQLZNKR-RJRFIUFISA-N (Z)-3-[3-[3, 5-bis (trifluoromethyl) phenyl]-1, 2, 4-triazol-
1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide Chemical group FC (F)(F) C1= CC (C (F)(F) F) …

2-pyrazine carboxamides as spleen tyrosine kinase inhibitors

MD Altman, B Cash, JM Ellis, ML Maddess… - US Patent …, 2017 - Google Patents
The invention provides certain pyrazine-2-carboxamide compounds of the Formula (I) or
pharmaceutically accept able salts thereof, wherein A, B, and X are as defined herein. The …