Patients with ischemic heart disease receiving reperfusion therapy still need to face left
ventricular remodeling and heart failure after myocardial infarction. Reperfusion itself …

Background Cardiovascular disease (CVD) remains the leading cause of morbidity and
mortality worldwide, imposing an enormous economic burden on individuals and human …

Glyphosate (GLY), one of the most extensively used herbicides in the world, has been
shown to inhibit testosterone synthesis in male animals. Mitochondria are crucial organelles …

Type 2 diabetic hearts are more vulnerable to myocardial ischemia reperfusion (MIR) injury,
which involves decreased mitophagy status with unknown mechanisms. MitoQ, a …

The imbalance of mitochondrial fission and fusion dynamics causes ischemic cardiomyocyte
apoptosis and heart injury by affecting mitophagy. Regulation of mitochondrial dynamics is …

Mitophagy is a form of autophagy that selectively removes damaged mitochondria and
attenuates mitochondrial-dependent apoptosis during viral infection, but how arboviruses …

Mitochondrial dynamics are critical for maintaining mitochondrial morphology and function
during cardiac ischemia and reperfusion (I/R). The immunoproteasome complex is an …

Background Acute myocardial infarction (AMI) is one of the leading causes of mortality
worldwide. Undesirable myocardial damage may occur during reperfusion of the ischemic …

Understanding the complex pathogenesis in myocardial ischemia/reperfusion (I/R) injury
(IRI) is an urgent problem in clinical trials. Increasing pieces of evidence have suggested …

Heart failure, mostly associated with cardiac hypertrophy, is a major cause of illness and
death. Oxidative stress causes accumulation of reactive oxygen species (ROS), leading to …