The physiological functions of human peroxisomes

RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Molecular insights into peroxisome homeostasis and peroxisome biogenesis disorders

Y Fujiki, K Okumoto, M Honsho, Y Abe - Biochimica et Biophysica Acta …, 2022 - Elsevier
Peroxisomes are single-membrane organelles essential for cell metabolism including the β-
oxidation of fatty acids, synthesis of etherlipid plasmalogens, and redox homeostasis …

Peroxisome assembly: matrix and membrane protein biogenesis

C Ma, G Agrawal, S Subramani - Journal of Cell Biology, 2011 - rupress.org
The biogenesis of peroxisomal matrix and membrane proteins is substantially different from
the biogenesis of proteins of other subcellular compartments, such as mitochondria and …

Peroxisome biogenesis in mammalian cells

Y Fujiki, K Okumoto, S Mukai, M Honsho… - Frontiers in …, 2014 - frontiersin.org
To investigate peroxisome assembly and human peroxisome biogenesis disorders (PBDs)
such as Zellweger syndrome, thirteen different complementation groups (CGs) of Chinese …

Peroxisome biogenesis, membrane contact sites, and quality control

JC Farré, SS Mahalingam, M Proietto, S Subramani - EMBO reports, 2019 - embopress.org
Peroxisomes are conserved organelles of eukaryotic cells with important roles in cellular
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …

[HTML][HTML] Protein import machineries of peroxisomes

R Rucktäschel, W Girzalsky, R Erdmann - Biochimica et Biophysica Acta …, 2011 - Elsevier
Peroxisomes are a class of structurally and functionally related organelles present in almost
all eukaryotic cells. The importance of peroxisomes for human life is highlighted by severe …

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p-and Pex16p-dependent pathway

T Matsuzaki, Y Fujiki - The Journal of cell biology, 2008 - rupress.org
Two distinct pathways have recently been proposed for the import of peroxisomal membrane
proteins (PMPs): a Pex19p-and Pex3p-dependent class I pathway and a Pex19p-and Pex3p …

The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy

S Yamashita, K Abe, Y Tatemichi, Y Fujiki - Autophagy, 2014 - Taylor & Francis
Peroxisomes are degraded by a selective type of autophagy known as pexophagy. Several
different types of pexophagy have been reported in mammalian cells. However, the …

Peroxisome: metabolic functions and biogenesis

K Okumoto, S Tamura, M Honsho, Y Fujiki - … Biology: Experimental Models …, 2020 - Springer
Peroxisome is an organelle conserved in almost all eukaryotic cells with a variety of
functions in cellular metabolism, including fatty acid β-oxidation, synthesis of ether …

A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum

SK Lam, N Yoda, R Schekman - Proceedings of the …, 2010 - National Acad Sciences
Pex19p, a soluble cytoplasmic transport protein, is required for the traffic of the peroxisomal
membrane proteins Pex3p and Pex15p from the endoplasmic reticulum (ER) to the …