Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

Abstract Purpose of Review This review provides an update on the role of gut hormones and
their interactions in the regulation of energy homeostasis, describes gut hormone …

Although SARS-CoV-2 can invade the intestine, though its effect on digestion and
absorption is not fully understood. In the present study, 56 COVID-19 patients and 47 age …

In primates including humans, the orbitofrontal cortex is the key brain region representing
the reward value and subjective pleasantness of the sight, smell, taste and texture of food. At …

Anorexia nervosa is a psychiatric disorder defined by an extremely low body weight, a
devastating fear of weight gain, and body image disturbance, however the etiopathogenesis …

The vagus nerve, a key component of the cross-communication between the gut and the
brain, is a major element of homeostasis sensing the “milieu intérieur” and boosting the …

Discovered 20 years ago, fibroblast growth factor (FGF) 19, and its mouse ortholog FGF15,
were the first members of a new subfamily of FGFs able to act as hormones. During fetal life …

The prevalence of overweight and obesity is continually increasing worldwide. Obesity is a
major public health concern given the multiple associated comorbidities. Finding dietary …

Any explanation of appetite control should contain a description of physiological processes
that could contribute a drive to eat alongside those that inhibit eating. However, such an …

The equilibrium and reciprocal actions among appetite-stimulating (orexigenic) and appetite-
suppressing (anorexigenic) signals synthesized in the gut, brain, microbiome and adipose …