Acute ischemic stroke therapy overview

L Catanese, J Tarsia, M Fisher - Circulation research, 2017 - Am Heart Assoc
The treatment of acute ischemic stroke has undergone dramatic changes recently
subsequent to the demonstrated efficacy of intra-arterial (IA) device-based therapy in …

The Alberta Stroke Program Early CT Score in clinical practice: what have we learned?

V Puetz, I Dzialowski, MD Hill… - International journal of …, 2009 - journals.sagepub.com
The introduction of brain imaging with computed tomography revolutionised the treatment of
patients with acute ischaemic stroke. With the visual differentiation of haemorrhagic stroke …

Association of clinical, imaging, and thrombus characteristics with recanalization of visible intracranial occlusion in patients with acute ischemic stroke

BK Menon, FS Al-Ajlan, M Najm, J Puig, M Castellanos… - Jama, 2018 - jamanetwork.com
Importance Recanalization of intracranial thrombus is associated with improved clinical
outcome in patients with acute ischemic stroke. The association of intravenous alteplase …

Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data

L San Román, BK Menon, J Blasco… - The Lancet …, 2018 - thelancet.com
Background Evidence regarding whether imaging can be used effectively to select patients
for endovascular thrombectomy (EVT) is scarce. We aimed to investigate the association …

Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry)

IGH Jansen, MJHL Mulder, RJB Goldhoorn - bmj, 2018 - bmj.com
Objective To determine outcomes and safety of endovascular treatment for acute ischaemic
stroke, due to proximal intracranial vessel occlusion in the anterior circulation, in routine …

Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke: real-world experience and a call for action

R Bhatia, MD Hill, N Shobha, B Menon, S Bal, P Kochar… - stroke, 2010 - Am Heart Assoc
Background and Purpose—Acute rates of recanalization after intravenous (IV) recombinant
tissue plasminogen activator (rt-PA) in proximal vessel occlusion have been estimated …

The importance of size: successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length

CH Riedel, P Zimmermann, U Jensen-Kondering… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—We hypothesize that in acute middle cerebral artery stroke,
thrombus lengths measured in thin-slice nonenhanced CT images define a limit beyond …

Time to reperfusion and treatment effect for acute ischemic stroke: a randomized clinical trial

PSS Fransen, OA Berkhemer, HF Lingsma… - JAMA …, 2016 - jamanetwork.com
Importance Intra-arterial treatment (IAT) for acute ischemic stroke caused by intracranial
arterial occlusion leads to improved functional outcome in patients treated within 6 hours …

CT angiography clot burden score and collateral score: correlation with clinical and radiologic outcomes in acute middle cerebral artery infarct

IYL Tan, AM Demchuk, J Hopyan… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Clot extent, location, and collateral integrity are important
determinants of outcome in acute stroke. We hypothesized that a novel clot burden score …

Association of time from stroke onset to groin puncture with quality of reperfusion after mechanical thrombectomy: a meta-analysis of individual patient data from 7 …

R Bourcier, M Goyal, DS Liebeskind, KW Muir… - JAMA …, 2019 - jamanetwork.com
Importance Reperfusion is a key factor for clinical outcome in patients with acute ischemic
stroke (AIS) treated with endovascular thrombectomy (EVT) for large-vessel intracranial …