Humans do not produce uricase, an enzyme responsible for degrading uric acid. However,
some bacteria residing in the gut can degrade one-third of the dietary and endogenous uric …

Hibernation is a mammalian strategy that uses metabolic plasticity to reduce energy
demands and enable long-term fasting. Fasting mitigates winter food scarcity but eliminates …

Amino acid homeostasis is maintained by import, export, oxidation, and synthesis of
nonessential amino acids, and by the synthesis and breakdown of protein. These processes …

Background An emerging strategy to treat symptoms of gastrointestinal (GI) dysmotility
utilizes the administration of isolated bacteria. However, the underlying mechanisms of …

Lactobacillus LB is a postbiotic generated following fermentation by Limosilactobacillus
fermentum and Lactobacillus delbrueckii. Lactobacillus LB alleviates acute diarrhoea and …

Diet can affect health and longevity by altering the gut microbiome profile. Sulfur amino acid
restriction (SAAR), like caloric restriction, extends lifespan. But, its effect on the gut …

ATB 0,+(SLC6A14) is a member of the amino acid transporter branch of the SLC6 family
along with GlyT1 (SLC6A9) and GlyT2 (SLC6A5), two glycine-specific transporters coupled …

Important precursors of monoaminergic neurotransmitters, dietary tryptophan (TRP),
tyrosine, and phenylalanine (all referred to as TTP), play crucial roles in a wide range of …

Abstract Background Claudins (CLDNs), major components of tight junctions, control
paracellular permeabilities of mineral ions and wastes. The absorption of nutrients including …

The large intestine plays a pivotal role in water and electrolyte balance. Paracellular
transport may play a role in ion transport mechanisms in the cecum and large intestine; …