[HTML][HTML] CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances

KM Maalej, M Merhi, VP Inchakalody, S Mestiri… - Molecular Cancer, 2023 - Springer
In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach to fight cancers. This approach consists of …

[HTML][HTML] Radiomics-based prediction of two-year clinical outcome in locally advanced cervical cancer patients undergoing neoadjuvant chemoradiotherapy

R Autorino, B Gui, G Panza, L Boldrini, D Cusumano… - La radiologia …, 2022 - Springer
Purpose The aim of this study is to determine if radiomics features extracted from staging
magnetic resonance (MR) images could predict 2-year long-term clinical outcome in patients …

[HTML][HTML] Advanced magnetic resonance imaging (MRI) techniques: technical principles and applications in nanomedicine

F Bruno, V Granata, F Cobianchi Bellisari, F Sgalambro… - Cancers, 2022 - mdpi.com
Simple Summary Magnetic Resonance Imaging (MRI) is a consolidated imaging tool for the
multiparametric assessment of tissues in various pathologies from degenerative and …

[HTML][HTML] Ionizable drug delivery systems for efficient and selective gene therapy

YQ Zhang, RR Guo, YH Chen, TC Li, WZ Du… - Military Medical …, 2023 - Springer
Gene therapy has shown great potential to treat various diseases by repairing the abnormal
gene function. However, a great challenge in bringing the nucleic acid formulations to the …

[HTML][HTML] Radiomics in colorectal cancer patients

R Inchingolo, C Maino, R Cannella… - World Journal of …, 2023 - ncbi.nlm.nih.gov
The main therapeutic options for colorectal cancer are surgical resection and adjuvant
chemotherapy in non-metastatic disease. However, the evaluation of the overall adjuvant …

Tumor microenvironment-activated, immunomodulatory nanosheets loaded with copper (II) and 5-FU for synergistic chemodynamic therapy and chemotherapy

Y Xia, M Gu, J Wang, X Zhang, T Shen, X Shi… - Journal of Colloid and …, 2024 - Elsevier
The tumor microenvironment (TME) has a redox state that differs greatly from normal tissues,
as characterized by the overexpression of H 2 O 2 and glutathione (GSH). To address the …

Gold nanoparticles-mediated photothermal and photodynamic therapies for cancer

SNT Koc, SR Benam, IP Aral, R Shahbazi… - International Journal of …, 2024 - Elsevier
Cancer remains one of the major causes of death globally, with one out of every six deaths
attributed to the disease. The impact of cancer is felt on psychological, physical, and …

Design Strategies of Tumor‐Targeted Delivery Systems Based on 2D Nanomaterials

L Ding, M Liang, C Li, X Ji, J Zhang, W Xie… - Small …, 2022 - Wiley Online Library
Conventional chemotherapy and radiotherapy are nonselective and nonspecific for cell
killing, causing serious side effects and threatening the lives of patients. It is of great …

Dynamic contrast-enhanced (DCE) imaging: state of the art and applications in whole-body imaging

D Albano, F Bruno, A Agostini, SA Angileri… - Japanese Journal of …, 2022 - Springer
Dynamic contrast-enhanced (DCE) imaging is a non-invasive technique used for the
evaluation of tissue vascularity features through imaging series acquisition after contrast …

[HTML][HTML] Preparation and investigation of a novel combination of Solanum nigrum-loaded, arabinoxylan-cross-linked β-cyclodextrin nanosponges for the treatment of …

HS Shah, S Zaib, I Khan, MA Sliem, O Alharbi… - Frontiers in …, 2023 - frontiersin.org
Introduction: Cancer contributes to a high mortality rate worldwide spanning its diversity from
genetics to resistant therapeutic response. To date emerging strategies to combat and …