Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium)-induced hepatotoxicity–A review
K Renu, R Chakraborty, H Myakala, R Koti… - Chemosphere, 2021 - Elsevier
Heavy metals pose a serious threat if they go beyond permissible limits in our bodies. Much
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …
[HTML][HTML] An update of Nrf2 activators and inhibitors in cancer prevention/promotion
F Pouremamali, A Pouremamali, M Dadashpour… - Cell Communication and …, 2022 - Springer
Abstract NF-E2-related factor 2 (Nrf2) protein is a basic-region leucine zipper transcription
factor that defends against endogenous or exogenous stressors. By inducing several …
factor that defends against endogenous or exogenous stressors. By inducing several …
[HTML][HTML] Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway
Z Qiongyue, Y Xin, P Meng, M Sulin, W Yanlin… - Frontiers in …, 2022 - frontiersin.org
Kidney is one of the most vulnerable organs in sepsis, resulting in sepsis-associated acute
kidney injury (SA-AKI), which brings about not only morbidity but also mortality of sepsis …
kidney injury (SA-AKI), which brings about not only morbidity but also mortality of sepsis …
From nature to therapy: Luteolin's potential as an immune system modulator in inflammatory disorders
Inflammation is an essential immune response that helps fight infections and heal tissues.
However, chronic inflammation has been linked to several diseases, including cancer …
However, chronic inflammation has been linked to several diseases, including cancer …
Dietary melatonin attenuates chromium-induced lung injury via activating the Sirt1/Pgc-1α/Nrf2 pathway
B Han, S Li, Y Lv, D Yang, J Li, Q Yang, P Wu, Z Lv… - Food & function, 2019 - pubs.rsc.org
Exposure to chromium (Cr) causes a number of respiratory diseases, including lung cancer
and pulmonary fibrosis. However, there is currently no safe treatment for Cr-induced lung …
and pulmonary fibrosis. However, there is currently no safe treatment for Cr-induced lung …
[HTML][HTML] Regulation of Nrf2/ARE pathway by dietary flavonoids: a friend or foe for cancer management?
The nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE)
pathway is an important cell signaling mechanism in maintaining redox homeostasis in …
pathway is an important cell signaling mechanism in maintaining redox homeostasis in …
Protective effects of morin against acrylamide-induced hepatotoxicity and nephrotoxicity: A multi-biomarker approach
Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …
to cooking or other thermal processes. The aim of present study was to assess the probable …
Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis
Objective Mercury is a global environmental pollutant and is responsible for several organ
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
Toxicological effects of deltamethrin on quail cerebrum: weakened antioxidant defense and enhanced apoptosis
J Li, H Jiang, P Wu, S Li, B Han, Q Yang, X Wang… - Environmental …, 2021 - Elsevier
Deltamethrin is the most common type II synthetic pyrethroid insecticide, and has posed
widespread residues to environment. However, whether deltamethrin has potential toxic …
widespread residues to environment. However, whether deltamethrin has potential toxic …
[HTML][HTML] Galangin Reverses H2O2-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling
JJ Lee, SC Ng, JY Hsu, H Liu, CJ Chen… - International Journal of …, 2022 - mdpi.com
UV radiation and H2O2 are the primary factors that cause skin aging. Both trigger oxidative
stress and cellular aging. It has been reported that deacetylase silent information regulator 1 …
stress and cellular aging. It has been reported that deacetylase silent information regulator 1 …