Abstract The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal
transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell …

Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

Cancer is the second leading cause of human death globally. PI3K/Akt/mTOR signaling is
one of the most frequently dysregulated signaling pathways observed in cancer patients that …

The intricate molecular pathways governing cancer development and progression have
spurred intensive investigations into novel therapeutic targets. Glycogen Synthase Kinase-3 …

To defense harmful stimuli or maintain the immune homeostasis, the body produces and
recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among …

Abstract Phosphoinositide-3 kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
signaling pathway is one of the most important proliferative signaling pathways with critical …

Tumors evade immune surveillance by expressing Programmed Death-Ligand 1 (PD-L1),
subsequently inhibiting CD8+ cytotoxic T lymphocyte function. Response of gastric cancer to …

The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …

Cancer is a complex ailment orchestrated by numerous intrinsic and extrinsic pathways.
Recent research has displayed a deep interest in developing plant-based cancer …

Simple Summary Chemotherapy resistance is a common occurrence during cancer
treatment that cancer researchers are attempting to understand and overcome. Mitochondria …