The anaerobic Gram-negative bacterium Porphyromonas gingivalis is considered the
keystone of periodontitis diseases, a set of inflammatory conditions that affects the tissues …

Arguably periodontitis is the most prevalent bacteria-driven chronic inflammatory disease of
the humankind. The incidence of periodontal disease has been reported to range from 30 …

Periodontal disease is a disease of tooth-supporting tissues. It is a chronic disease with
inflammatory nature and infectious etiology produced by a dysbiotic subgingival microbiota …

Porphyromonas gingivalis, a periodontal pathogen, secretes outer membrane vesicles
(MVs) that contain major virulence factors, including proteases termed gingipains (Arg …

Background Porphyromonas gingivalis, a periodontal pathogen, expresses a number of
virulence factors, including long (FimA) and short (Mfa) fimbriae as well as gingipains …

The type IX secretion system (T9SS) is a multiprotein machine distributed in Bacteroidota
and responsible for the secretion of various proteins across the outer membrane. Secreted …

The cytokine IL-33 is constitutively expressed in epithelial cells and it augments Th2
cytokine-mediated inflammatory responses by regulating innate immune cells. We aimed to …

We recently reported that the oral mucosal pathogen Porphyromonas gingivalis, through its
67-kDa Mfa1 (minor) fimbria, targets the C-type lectin receptor DC-SIGN for invasion and …

Porphyromonas gingivalis has been shown to accelerate atherosclerotic lesion
development in hyperlipidemic animals. Atherosclerosis is a disease characterized by …

Porphyromonas gingivalis is one of the well-characterized periodontal pathogens involved
in periodontitis. The invasive and proteolytic activities of P. gingivalis clinical isolates have …