Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Neural stem cells in the adult mammalian brain are the source of new neurons that
contribute to complex sensory and cognitive functions. Most adult neural stem cells are …

Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …

In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …

Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …

It is well established that estrogens affect neuroplasticity in a number of brain regions. In
particular, estrogens modulate and mediate spine and synapse formation as well as …

Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside
within distinct regions of the brain. This phenomenon was first described over 50 years ago …

The hippocampus is a highly stress susceptible structure and hippocampal abnormalities
have been reported in a host of psychiatric disorders including major depression and post …

Sex differences in the function of the hippocampus have been observed in numerous
mammalian species. However, the magnitude, extent, and specificity of these differences are …

Women constitute half of the world's population, yet neuroscience research does not serve
the sexes equally. Fifty years of preclinical animal evidence documents the tightly-coupled …