Chronic kidney disease (CKD) is an important global public health problem due to its high
prevalence and morbidity. Although the treatment of nephrology patients has changed …

The concept of immunosuppression to support allograft longevity was introduced in the early
twentieth century, yet most therapeutic advances have occurred over the past few decades …

Background Large interindividual variations have been reported in chemotherapy‐induced
toxicities. Little is known whether racial disparities exist in neutropenia associated with …

In clinical practice, owing to the comprehensive genetic insights they offer, haplotypes have
attracted greater attention than individual single nucleotide polymorphisms (SNPs). Due to …

Background The purpose of the study was to develop a genotype-incorporated population
pharmacokinetic (PPK) model of tacrolimus (TAC) in adults with systemic lupus …

Mycophenolic acid exhibits significant interpatient pharmacokinetic variability attributed to
factors including race, sex, concurrent medications, and enterohepatic circulation of the …

Kidney allograft survival remains poorer in Black compared to White recipients due to racial
differences in calcineurin inhibitor (CNI) pharmacology. P‐glycoprotein (P‐gp), an ABC …

Oxycodone (brand names OxyContin, Roxicodone, Xtampza ER, and Oxaydo), is an opioid
analgesic used for moderate to severe pain caused by various conditions for which …

En este estudio se examinó la prevalencia de las interacciones medicamentosas (IM) de los
fármacos inmunosupresores con impacto clínico real en pacientes trasplantados ingresados …