Mechanisms of MHC class I–restricted antigen processing

E Pamer, P Cresswell - Annual review of immunology, 1998 - annualreviews.org
▪ Abstract Classical class I molecules assemble in the endoplasmic reticulum (ER) with
peptides mostly generated from cytosolic proteins by the proteasome. The activity of the …

Molecular detection of pheromone signals in mammals: from genes to behaviour

C Dulac, AT Torello - Nature Reviews Neuroscience, 2003 - nature.com
The instinctive and species-specific behavioural response of animals to pheromones has
intrigued biologists for a long time. Recent molecular and electrophysiological approaches …

Functional requirement for class I MHC in CNS development and plasticity

GS Huh, LM Boulanger, H Du, PA Riquelme, TM Brotz… - Science, 2000 - science.org
Class I major histocompatibility complex (class I MHC) molecules, known to be important for
immune responses to antigen, are expressed also by neurons that undergo activity …

Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence–derived peptides by CD94/NKG2 confers protection …

F Borrego, M Ulbrecht, EH Weiss, JE Coligan… - The Journal of …, 1998 - rupress.org
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule,
the gene for which is transcribed in most tissues. It has recently been reported that this …

[PDF][PDF] MHC class I: an unexpected role in neuronal plasticity

CJ Shatz - Neuron, 2009 - cell.com
For the nervous system to translate experience into memory and behavior, lasting structural
change at synapses must occur. This requirement is clearly evident during critical periods of …

The human major histocompatibility complex class Ib molecule HLA‐E binds signal sequence‐derived peptides with primary anchor residues at positions 2 and 9

V Braud, E Yvonne Jones… - European journal of …, 1997 - Wiley Online Library
Human histocompatibility leukocyte antigen E (HLA‐E) and mouse major histocompatibility
complex (MHC) class Ib antigen, Qa‐1, share the same substitutions at two normally …

HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story

DJ Hicklin, FM Marincola, S Ferrone - Molecular medicine today, 1999 - cell.com
Human leukocyte antigen (HLA) class I molecule downregulation occurs frequently in many
cancers, and this abnormality might adversely affect the clinical course of cancer and the …

Antigen processing and presentation by the class I major histocompatibility complex

IA York, KL Rock - Annual review of immunology, 1996 - annualreviews.org
▪ Abstract Major histocompatibility complex (MHC) class I molecules bind peptides derived
from cellular proteins and display them for surveillance by the immune system. These …

[PDF][PDF] CD1d1 mutant mice are deficient in natural T cells that promptlyproduce IL-4

SK Mendiratta, WD Martin, S Hong, A Boesteanu… - Immunity, 1997 - cell.com
Murine CD1 has been implicated in the development and function of an unusual subset of T
cells, termed natural T (NT) cells, that coexpress the T cell receptor (TCR) and the natural …

Immunological relationship between the mother and the fetus

J Szekeres-Bartho - International reviews of immunology, 2002 - Taylor & Francis
The immunological relationship between the mother and the fetus is a bi-directional
communication determined on the one hand by fetal antigen presentation and on the other …