[HTML][HTML] Acute exposure to artificial light at night alters hippocampal vascular structure in mice

JR Bumgarner, WH Walker, DD Quintana, RC White… - Iscience, 2023 - cell.com
The structure and function of the cardiovascular system are modulated across the day by
circadian rhythms, making this system susceptible to circadian rhythm disruption. Recent …

Ingestion-time differences in the pharmacodynamics of dual-combination hypertension therapies: Systematic review and meta-analysis of published human trials

RG Hermida-Ayala, A Mojon… - Chronobiology …, 2022 - Taylor & Francis
The pharmacodynamics of hypertension medications can be significantly affected by
circadian rhythms in the biological mechanisms of the 24 h blood pressure (BP) pattern …

Guidelines for the design and conduct of human clinical trials on ingestion-time differences–chronopharmacology and chronotherapy–of hypertension medications

RC Hermida, MH Smolensky, H Balan… - Chronobiology …, 2021 - Taylor & Francis
Current hypertension guidelines fail to provide a recommendation on when-to-treat, thus
disregarding relevant circadian rhythms that regulate blood pressure (BP) level and 24 h …

Systematic review and quality evaluation of published human ingestion-time trials of blood pressure-lowering medications and their combinations

RC Hermida, RG Hermida-Ayala, A Mojon… - Chronobiology …, 2021 - Taylor & Francis
ABSTRACT The pharmacokinetics (PK)–absorption, distribution, metabolism, and
elimination–and pharmacodynamics (PD) of hypertension medications can be significantly …

Differences of blood pressure measured at clinic versus at home in the morning and in the evening in Europe and Asia: a systematic review and meta‐analysis

H Miao, S Yang, Y Zhang - The Journal of Clinical …, 2022 - Wiley Online Library
Numerous studies have indicated that there might be great differences among different
populations in Europe and Asia in terms of home morning and evening blood pressure (BP) …

Circadian clock signals in the adrenal cortex

T Ota, JM Fustin, H Yamada, M Doi… - Molecular and cellular …, 2012 - Elsevier
Circadian secretion of steroid hormones by the adrenal cortex is required to maintain whole
body homeostasis and to adequately respond to or anticipate environmental changes. The …

Diurnal variation of endothelial function and arterial stiffness in hypertension

GE Kollias, KS Stamatelopoulos… - Journal of human …, 2009 - nature.com
The onset of cardiovascular events presents a circadian variation that may be mediated by
similar temporal patterns of vascular function. Blood pressure also follows circadian …

Molecular bases of circadian rhythmicity in renal physiology and pathology

O Bonny, M Vinciguerra, ML Gumz… - Nephrology Dialysis …, 2013 - academic.oup.com
The physiological processes that maintain body homeostasis oscillate during the day.
Diurnal changes characterize kidney functions, comprising regulation of hydro-electrolytic …

Epidemiology and chronobiology of out-of-hospital cardiac arrest in a subpopulation of southern Poland: A two-year observation

S Szczerbinski, J Ratajczak, P Lach… - Cardiology …, 2020 - journals.viamedica.pl
Background: Although recent studies indicate temporal variations in the incidence of out-of-
hospital cardiac arrest (OHCA), the Polish experience in this research is scarce to date. We …

Does timing of antihypertensive medication dosing matter?

RC Hermida, RG Hermida-Ayala… - Current Cardiology …, 2020 - Springer
Abstract Purpose of Review Current hypertension guidelines do not provide
recommendation on when-to-treat. Herein, we review the current evidence on ingestion-time …