During the past decade, accumulating evidence from the research highlights the suggested
effects of bacterial communities of the human gut microbiota and their metabolites on health …

Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis
point to distinct immunological pathways that drive disease relapses and progression. In …

Growing empirical evidence suggests that nutrition and bacterial metabolites might impact
the systemic immune response in the context of disease and autoimmunity. We report that …

Multiple sclerosis (MS) is the most frequent chronic inflammatory disease of the CNS, and
imposes major burdens on young lives. Great progress has been made in understanding …

A vast number of studies have demonstrated a remarkable role for the gut microbiota and
their metabolites in the pathogenesis of inflammatory diseases, including multiple sclerosis …

Multiple sclerosis (MS) shares an immune-mediated origin with psoriasis. Long-term safety
and efficacy data generated in Europe from usage of fumaric acid formulations in the latter …

Short-chain fatty acids are processed from indigestible dietary fibers by gut bacteria and
have immunomodulatory properties. Here, we investigate propionic acid (PA) in multiple …

Identification of the target antigens of pathogenic antibodies and T cells is of fundamental
importance for understanding the pathogenesis of multiple sclerosis, and for the …

Importance Natalizumab reduces multiple sclerosis relapses very effectively; however,
severe disease activity may return once natalizumab treatment is withdrawn, as …

Multiple sclerosis (MS), a demyelinating disease of the central nervous system (CNS),
presents as a complex disease with variable clinical and pathological manifestations …