Fluorescence correlation spectroscopy (FCS) is a powerful technique for quantification of
molecular dynamics, and it has been widely applied in diverse fields, eg, biomedicine …

Cells within developing tissues rely on morphogens to assess positional information.
Passive diffusion is the most parsimonious transport model for long-range morphogen …

Identifying key players and their interactions is fundamental for understanding biochemical
mechanisms at the molecular level. The ever-increasing number of alternative ways to …

Intracellular diffusion underlies vital cellular processes. However, it remains difficult to
elucidate how an unbound protein diffuses inside the cell with good spatial resolution and …

Fluorescence correlation spectroscopy (FCS) is a single molecule sensitive tool for the
quantitative measurement of biomolecular dynamics and interactions. Improvements in …

While fundamentally important, the intracellular diffusion of small (≲ 1 kDa) solutes has been
difficult to elucidate due to challenges in both labeling and measurement. Here we quantify …

In living cells, most proteins diffuse over distances of micrometres within seconds. Protein
translocation is constrained due to the cellular organization into subcompartments that …

While critical to biological processes, molecular diffusion is difficult to quantify, and spatial
mapping of local diffusivity is even more challenging. Here we report a machine-learning …

The analysis of protein interaction networks is one of the key challenges in the study of
biology. It connects genotypes to phenotypes, and disruption often leads to diseases …

Protein–protein interactions (PPIs) represent an essential aspect of plant systems biology.
Identification of key protein players and their interaction networks provide crucial insights …