Global HIV neurology: a comprehensive review

KT Thakur, A Boubour, D Saylor, M Das, DR Bearden… - Aids, 2019 - journals.lww.com
Neurological conditions associated with HIV remain major contributors to morbidity and
mortality and are increasingly recognized in the aging population on long-standing …

[HTML][HTML] Beneficial and adverse effects of cART affect neurocognitive function in HIV-1 infection: balancing viral suppression against neuronal stress and injury

NY Yuan, M Kaul - Journal of Neuroimmune Pharmacology, 2021 - Springer
HIV-associated neurocognitive disorders (HAND) persist despite the successful introduction
of combination antiretroviral therapy (cART). While insufficient concentration of certain …

HIV-associated neurotoxicity and cognitive decline: Therapeutic implications

DR Wallace - Pharmacology & Therapeutics, 2022 - Elsevier
As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …

Brain-accumulating nanoparticles for assisting astrocytes to reduce human immunodeficiency virus and drug abuse-induced neuroinflammation and oxidative stress

B Surnar, AS Shah, M Park, AA Kalathil, MZ Kamran… - ACS …, 2021 - ACS Publications
Human neurotropic immunodeficiency virus (HIV) ingress into the brain and its subsequent
replication after infection results in viral reservoirs in the brain. The infected cells include …

HIV-1 gp120-induced endolysosome de-acidification leads to efflux of endolysosome iron, and increases in mitochondrial iron and reactive oxygen species

PW Halcrow, KL Lakpa, N Khan, Z Afghah… - Journal of Neuroimmune …, 2021 - Springer
The HIV-1 coat protein gp120 continues to be implicated in the pathogenesis of HIV-1
associated neurocognitive disorder (HAND); a condition known to affect~ 50% of people …

[HTML][HTML] Extracellular vesicles: a possible link between HIV and Alzheimer's disease-like pathology in HIV subjects?

S Kodidela, K Gerth, S Haque, Y Gong, S Ismael… - Cells, 2019 - mdpi.com
The longevity of people with HIV/AIDS has been prolonged with the use of antiretroviral
therapy (ART). The age-related complications, especially cognitive deficits, rise as HIV …

HIV neuropathogenesis in the presence of a disrupted dopamine system

EA Nickoloff-Bybel, TM Calderon, PJ Gaskill… - Journal of Neuroimmune …, 2020 - Springer
Antiretroviral therapy (ART) has transformed HIV into a chronic condition, lengthening and
improving the lives of individuals living with this virus. Despite successful suppression of HIV …

Human immunodeficiency virus type 1 and methamphetamine-mediated mitochondrial damage and neuronal degeneration in human neurons

C Teodorof-Diedrich, SA Spector - Journal of virology, 2020 - Am Soc Microbiol
Methamphetamine, a potent psychostimulant, is a highly addictive drug commonly used by
persons living with HIV (PLWH), and its use can result in cognitive impairment and memory …

Mental health and cognition in relation to adherence to antiretroviral therapy among people living with HIV in Kazakhstan: a cross‐sectional study

G Mergenova, A Davis, L Gilbert… - Journal of the …, 2024 - Wiley Online Library
Introduction There is a research gap in how mental health and cognition are associated with
antiretroviral treatment (ART) adherence among people living with HIV (PLWH) in …

[HTML][HTML] Neurological, Behavioral, and Pathophysiological Characterization of the Co-Occurrence of Substance Use and HIV: A Narrative Review

L Vines, D Sotelo, N Giddens, P Manza, ND Volkow… - Brain Sciences, 2023 - mdpi.com
Combined antiretroviral therapy (cART) has greatly reduced the severity of HIV-associated
neurocognitive disorders in people living with HIV (PLWH); however, PLWH are more likely …