[HTML][HTML] Multiorgan-on-a-chip: a systemic approach to model and decipher inter-organ communication

N Picollet-D'hahan, A Zuchowska, I Lemeunier… - Trends in …, 2021 - cell.com
Multiorgan-on-a-chip (multi-OoC) platforms have great potential to redefine the way in which
human health research is conducted. After briefly reviewing the need for comprehensive …

[HTML][HTML] Use of human umbilical vein endothelial cells (HUVEC) as a model to study cardiovascular disease: A review

DJ Medina-Leyte, M Domínguez-Pérez, I Mercado… - Applied Sciences, 2020 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death worldwide, and extensive
research has been performed to understand this disease better, using various experimental …

Microphysiological engineering of self-assembled and perfusable microvascular beds for the production of vascularized three-dimensional human microtissues

J Paek, SE Park, Q Lu, KT Park, M Cho, JM Oh… - ACS …, 2019 - ACS Publications
The vasculature is an essential component of the circulatory system that plays a vital role in
the development, homeostasis, and disease of various organs in the human body. The …

Green tea (Camellia sinensis) and l-theanine: Medicinal values and beneficial applications in humans—A comprehensive review

M Saeed, M Naveed, M Arif, MU Kakar… - Biomedicine & …, 2017 - Elsevier
Green tea (Camellia sinensis) is a famous herb, and its extract has been extensively used in
traditional Chinese medicinal system. In this context, several studies have revealed its …

Carcinogenic microbiota and its role in colorectal cancer development

TM Karpiński, M Ożarowski, M Stasiewicz - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of the most common malignancies worldwide. The main risk
factors for CRC are family history of colon or rectal cancer, familial polyposis syndrome or …

Destruction of tumor vasculature by vascular disrupting agents in overcoming the limitation of EPR effect

Z Liu, Y Zhang, N Shen, J Sun, Z Tang… - Advanced Drug Delivery …, 2022 - Elsevier
Nanomedicine greatly improves the efficiency in the delivery of antitumor drugs into the
tumor, but insufficient tumoral penetration impairs the therapeutic efficacy of most …

[HTML][HTML] Vasculature-on-a-chip for in vitro disease models

S Kim, W Kim, S Lim, JS Jeon - Bioengineering, 2017 - mdpi.com
Vascularization, the formation of new blood vessels, is an essential biological process. As
the vasculature is involved in various fundamental physiological phenomena and closely …

[HTML][HTML] Emerging roles of hydrogen sulfide in inflammatory and neoplastic colonic diseases

FF Guo, TC Yu, J Hong, JY Fang - Frontiers in physiology, 2016 - frontiersin.org
Hydrogen sulfide (H 2 S) is a toxic gas that has been recognized as an important mediator of
many physiological processes, such as neurodegeneration, regulation of inflammation …

[HTML][HTML] Epigallocatechin gallate nanodelivery systems for cancer therapy

A Granja, M Pinheiro, S Reis - Nutrients, 2016 - mdpi.com
Cancer is one of the leading causes of morbidity and mortality all over the world.
Conventional treatments, such as chemotherapy, are generally expensive, highly toxic and …

[HTML][HTML] Fabrication of three-dimensional biomimetic microfluidic networks in hydrogels

KA Heintz, ME Bregenzer, JL Mantle… - Advanced healthcare …, 2016 - ncbi.nlm.nih.gov
A laser-based hydrogel degradation technique was developed that allowed for local control
over hydrogel porosity; fabrication of 3D vascular-derived, biomimetic, hydrogel-embedded …