Nanomedicine targeting ferroptosis to overcome anticancer therapeutic resistance
A potential reason for the failure of tumor therapies is treatment resistance. Resistance to
chemotherapy, radiotherapy, and immunotherapy continues to be a major obstacle in clinic …
chemotherapy, radiotherapy, and immunotherapy continues to be a major obstacle in clinic …
The roles of ferroptosis in cancer: tumor suppression, tumor microenvironment, and therapeutic interventions
In cancer treatment, the recurrent challenge of inducing apoptosis through conventional
therapeutic modalities, often thwarted by therapy resistance, emphasizes the critical need to …
therapeutic modalities, often thwarted by therapy resistance, emphasizes the critical need to …
A multifunctional covalent organic framework nanozyme for promoting ferroptotic radiotherapy against esophageal cancer
LL Zhou, Q Guan, W Zhou, JL Kan, K Teng, M Hu… - ACS …, 2023 - ACS Publications
Radiotherapy is inevitably accompanied by some degree of radiation resistance, which
leads to local recurrence and even therapeutic failure. To overcome this limitation, herein …
leads to local recurrence and even therapeutic failure. To overcome this limitation, herein …
Targeting Nrf2 for ferroptosis-based therapy: Implications for overcoming ferroptosis evasion and therapy resistance in cancer
J Lee, JL Roh - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2023 - Elsevier
Ferroptosis is a newly discovered form of programmed cell death caused by redox-active
iron-mediated lipid peroxidation. Ferroptosis exhibits a unique morphological phenotype …
iron-mediated lipid peroxidation. Ferroptosis exhibits a unique morphological phenotype …
Puerarin attenuates valproate-induced features of ASD in male mice via regulating Slc7a11-dependent ferroptosis
P Jiang, L Zhou, L Zhao, X Fei, Z Wang, T Liu… - …, 2024 - nature.com
Autism spectrum disorder (ASD) is a complicated, neurodevelopmental disorder
characterized by social deficits and stereotyped behaviors. Accumulating evidence suggests …
characterized by social deficits and stereotyped behaviors. Accumulating evidence suggests …
[HTML][HTML] Radiotherapy-induced ferroptosis for cancer treatment
GL Beretta, N Zaffaroni - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Ferroptosis is a regulated cell death mechanism controlled by iron, amino acid and reactive
oxygen species metabolisms, which is very relevant for cancer therapy. Radiotherapy …
oxygen species metabolisms, which is very relevant for cancer therapy. Radiotherapy …
Peptide‐Functionalized Inorganic Oxide Nanomaterials for Solid Cancer Imaging and Therapy
X Duan, P Wang, L He, Z He, S Wang… - Advanced …, 2024 - Wiley Online Library
The diagnosis and treatment of solid tumors have undergone significant advancements
marked by a trend toward increased specificity and integration of imaging and therapeutic …
marked by a trend toward increased specificity and integration of imaging and therapeutic …
Oxygen Vacancy‐Rich Manganese Nanoflowers as Ferroptosis Inducers for Tumor Radiotherapy
The combination of ferroptosis and innovative tumor therapy methods offers another
promising answer to the problem of tumors. In order to generate effective ferroptosis in tumor …
promising answer to the problem of tumors. In order to generate effective ferroptosis in tumor …
From ferroptosis to cuproptosis, and calcicoptosis, to find more novel metals-mediated distinct form of regulated cell death
J Gu, C Guo, J Ruan, K Li, Y Zhou, X Gong, H Shi - Apoptosis, 2024 - Springer
Regulated cell death (RCD), also known as programmed cell death (PCD), plays a critical
role in various biological processes, such as tissue injury/repair, development, and …
role in various biological processes, such as tissue injury/repair, development, and …
Progress and challenges in tumor ferroptosis treatment strategies: a comprehensive review of metal complexes and nanomedicine
Y Su, B Liu, B Wang, L Chan, C Xiong, L Lu, X Zhang… - Small, 2024 - Wiley Online Library
Ferroptosis is a new form of regulated cell death featuring iron‐dependent lipid peroxides
accumulation to kill tumor cells. A growing body of evidence has shown the potential of …
accumulation to kill tumor cells. A growing body of evidence has shown the potential of …