Macrophages are heterogeneous and their phenotype and functions are regulated by the
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …

The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Colorectal cancer (CRC) is among the most common malignancies with limited treatments
other than surgery. The tumor microenvironment (TME) profiling enables the discovery of …

Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

Macrophage polarization is increasingly recognised as an important pathogenetic factor in
inflammatory and neoplastic diseases. Proinflammatory M1 macrophages promote T helper …

Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack
antigen specificity and be devoid of immunological memory. Strategies that can induce …

Recurrent spontaneous abortion affects approximately 1–2% of women of childbearing, and
describes a condition in which women suffer from three or more continuous spontaneous …

Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Fungal pathogens can rarely cause diseases in immunocompetent individuals. However,
commensal and normally nonpathogenic environmental fungi can cause life-threatening …

Understanding the host immune response during cryptococcal meningitis (CM) is of critical
importance for the development of immunomodulatory therapies. We profiled the …