Cryptococcus species are fungal pathogens that are a leading cause of mortality. Initial
inoculation is through the pulmonary route and, if disseminated, results in severe invasive …

Macrophages serve as a first line of defense against microbial pathogens. Exposure to
interferon-γ (IFNγ) increases interferon-stimulated gene (ISG) expression in these cells …

Macrophage receptor with collagenous structure (MARCO) contributes to fungal
containment during the early/innate phase of cryptococcal infection; however, its role in …

Cryptococcus neoformans and Cryptococcus gattii, the predominant etiological agents of
cryptococcosis, are fungal pathogens that cause disease ranging from a mild pneumonia to …

In recent years, the frequency of influenza epidemics around the world has posed a great
threat to the lives of people, especially those in developing countries. However, it is unclear …

Cryptococcal meningitis is a fatal opportunistic infection of the brain and a leading cause of
neurological damage and death in immunocompromised individuals. This neglected fungal …

Cryptococcosis is a fungal disease primarily occurring in immunocompromised individuals,
such as AIDS patients, and is associated with high morbidity and mortality. However …

OBJECTIVE: The objective of this narrative review is to present a summary of current
knowledge of host-fungal pathogen interaction focusing on the importance of the innate …

Vitamin D deficiency may increase susceptibility to opportunistic infections in HIV-infected
individuals. We found no evidence that vitamin D deficiency increases risk of cryptococcal …

Disseminated cryptococcosis has a nearly 70% mortality, mostly attributed to CNS infection,
with lesser-known effects on other organs. Immune protection against Cryptococcus relies …