[HTML][HTML] Technologies for HIV-1 drug resistance testing: inventory and needs

KJ Metzner - Current Opinion in HIV and AIDS, 2022 - journals.lww.com
The use of NGS technologies on HIV DR testing will allow unprecedented insights into
genomic structures of virus populations that may be of immediate relevance to both clinical …

HIV-1 drug resistance genotyping in resource limited settings: current and future perspectives in sequencing technologies

S Manyana, L Gounder, M Pillay, J Manasa, K Naidoo… - Viruses, 2021 - mdpi.com
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …

Low-frequency pre-treatment HIV drug resistance: Effects on 2-year outcome of first-line efavirenz-based antiretroviral therapy

RS Milne, IA Beck, M Levine, I So, N Andersen… - Aids, 2022 - journals.lww.com
Objective (s): Assess the impact of pre-treatment high-frequency and low-frequency drug-
resistant HIV variants on long-term outcomes of first-line efavirenz-based antiretroviral …

[HTML][HTML] Laboratory diagnosis of HIV: a contemporary overview in the Australian context

E Williams, M Moso, C Lim, D Chibo, S Nicholson… - Pathology, 2023 - Elsevier
Over the past decade there have been technical advances in human immunodeficiency
virus (HIV) assays and updates to testing regulations that have substantially changed the …

Viral resistance burden and APOBEC editing correlate with virological response in heavily treatment-experienced people living with multi-drug resistant HIV

D Armenia, MM Santoro, MC Bellocchi, L Carioti… - International Journal of …, 2022 - Elsevier
Background The impact of drug resistance mutational load and APOBEC editing in heavily
treatment-experienced (HTE) people living with multidrug-resistant HIV has not been …

Advancing HIV drug resistance technologies and strategies: insights from South Africa's experience and future directions for resource-limited settings

K Steegen, GU van Zyl, M Claassen, A Khan, M Pillay… - Diagnostics, 2023 - mdpi.com
Monitoring of HIV drug resistance (HIVDR) remains critical for ensuring countries attain and
sustain the global goals for ending HIV as a public health threat by 2030. On an individual …

Strengths and caveats of identifying resistance genes from whole genome sequencing data

BM Forde, DMP De Oliveira, C Falconer… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Antimicrobial resistance (AMR) continues to present major challenges to
modern healthcare. Recent advances in whole-genome sequencing (WGS) have made the …

Portable Nanopore sequencing solution for next-generation HIV drug resistance testing

SY Park, G Faraci, K Ganesh, MP Dubé… - Journal of Clinical …, 2024 - Elsevier
Background Tackling HIV drug resistance is one of major challenges for ending AIDS
epidemic, but the elevated expense of cutting-edge genomics hampers the advancement of …

Performance of the Applied Biosystems HIV-1 Genotyping Kit with Integrase

HP Moore, PJ Palumbo, KI Notarte… - Journal of Clinical …, 2024 - Am Soc Microbiol
ABSTRACT HIV genotyping is used to assess HIV susceptibility to antiretroviral drugs. The
Applied Biosystems HIV-1 Genotyping Kit with Integrase (AB kit, Thermo Fisher Scientific) …

Protease and gag diversity and drug resistance mutations among treatment-naive Mexican people living with HIV

S Climaco-Arvizu, V Flores-López… - BMC Infectious …, 2022 - Springer
Abstract Introduction In Mexico, HIV genotyping is performed in people living with HIV
(PLWH) failing their first-line antiretroviral (ARV) regimen; it is not routinely done for all …