The role of microRNAs in the pathophysiology of human central nervous system: a focus on neurodegenerative diseases

D Rezaee, F Saadatpour, N Akbari, A Zoghi… - Ageing Research …, 2023 - Elsevier
Abstract microRNAs (miRNAs) are suggested to play substantial roles in regulating the
development and various physiologic functions of the central nervous system (CNS). These …

Non-coding RNAs/DNMT3B axis in human cancers: from pathogenesis to clinical significance

C Huang, P Azizi, M Vazirzadeh… - Journal of Translational …, 2023 - Springer
Cancer is a complex disease with many contributing factors, and researchers have gained
extensive knowledge that has helped them understand the diverse and varied nature of …

The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer

S Pordel, M Khorrami, F Saadatpour, D Rezaee… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

microRNA-184 in the landscape of human malignancies: a review to roles and clinical significance

M Fattahi, D Rezaee, F Fakhari, S Najafi… - Cell Death …, 2023 - nature.com
MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …

Liquid biopsy in colorectal cancer

S Najafi, J Majidpoor, K Mortezaee - Clinica Chimica Acta, 2023 - Elsevier
Liquid biopsy refers to a set of pathological samples retrieved from non-solid sources, such
as blood, cerebrospinal fluid, urine, and saliva through non-invasive or minimally invasive …

Microbiome modulation in inflammatory diseases: Progress to microbiome genetic engineering

F Mousavinasab, R Karimi, S Taheri… - Cancer Cell …, 2023 - Springer
Recent developments in sequencing technology and analytical approaches have allowed
researchers to show that the healthy gut microbiome is very varied and capable of …

LIPH contributes to glycolytic phenotype in pancreatic ductal adenocarcinoma by activating LPA/LPAR axis and maintaining ALDOA stability

L Han, Y Jiang, M Shi, L Gan, Z Wu, M Xue… - Journal of Translational …, 2023 - Springer
Background LIPH, a membrane-associated phosphatidic acid-selective phospholipase A1a,
can produce LPA (Lysophosphatidic acid) from PA (Phosphatidic acid) on the outer leaflet of …

Unraveling temporal and spatial biomarkers of epithelial-mesenchymal transition in colorectal cancer: insights into the crucial role of immunosuppressive cells

M Wang, C Deng, C Yang, M Yan, H Lu… - Journal of Translational …, 2023 - Springer
The occurrence and progression of tumors can be established through a complex interplay
among tumor cells undergoing epithelial-mesenchymal transition (EMT), invasive factors …

Evaluation of long non-coding RNA (LncRNA) in the pathogenesis of chemotherapy resistance in cervical cancer: diagnostic and prognostic approach

N Modabber, SS Mahboub, S Khoshravesh… - Molecular …, 2023 - Springer
Cervical cancer (CC), caused by human papillomavirus (HPV), is a leading cause of female
malignancies worldwide. Therefore, understanding the underlying mechanisms of CC …

Tumor-educated platelets

S Najafi, Y Asemani, J Majidpoor, R Mahmoudi… - Clinica Chimica …, 2023 - Elsevier
Beyond traditional roles in homeostasis and coagulation, growing evidence suggests that
platelets also reflect malignant transformation in cancer. Platelets are present in the tumor …