The microRNA Let-7 and its exosomal form: Epigenetic regulators of gynecological cancers

F Wang, C Zhou, Y Zhu, M Keshavarzi - Cell Biology and Toxicology, 2024 - Springer
Many types of gynecological cancer (GC) are often silent until they reach an advanced
stage, and are therefore often diagnosed too late for effective treatment. Hence, there is a …

miR-29a-SIRT1-Wnt/β-Catenin Axis Regulates Tumor Progression and Survival in Hepatocellular Carcinoma

L Qian, Y Zhang, G Wang, B Li, H Zhou, J Qiu… - Biochemical Genetics, 2023 - Springer
Abstract Sirtuin 1 (SIRT1) participates in the initiation and evolution of hepatocellular
carcinoma (HCC). However, the specific mechanism of SIRT1 in HCC remains unclear. The …

Withaferin A alters the expression of microRNAs 146a-5p and 34a-5p and associated hub genes in MDA-MB-231 cells

M Shuaib, S Chaudhri, S Kumar - Biomolecular Concepts, 2024 - degruyter.com
Triple-negative breast cancer (TNBC) is a highly metastatic subtype of breast cancer. Due to
the absence of obvious therapeutic targets, microRNAs (miRNAs) provide possible hope to …

CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis

J Luo, H Zhong, M Guo, P Xiao, R Cao… - … in Cancer Research …, 2024 - journals.sagepub.com
Objectives Circular RNAs (circRNAs) serve a crucial regulatory role in ovarian cancer (OC).
Circular RNA ArfGAP with FG repeats 1 (circAGFG1) has been shown to be involved in …

Sevoflurane Confers Protection Against the Malignant Phenotypes of Lung Cancer Cells via the microRNA-153-3p/HIF1α/KDM2B Axis

K Xiong, Z Wu - Biochemical Genetics, 2023 - Springer
Sevoflurane is shown to curtail lung cancer (LC) development. Herein, this research sought
to investigate the underlying mechanism of sevoflurane in regard to its repressive effects on …

circ_0006789 promotes cervical cancer development via the miR-615-5p/HSF1 axis

W Zhou, W Song, M Lu - Discover Oncology, 2024 - Springer
Objective Circular RNAs (circRNAs) are involved in the development of human cancers,
including cervical cancer (CC). However, the role and mechanism of circ_0006789 …

[HTML][HTML] Systems biology investigation of epithelial-mesenchymal transition in hepatocellular carcinoma pathogenesis

FA Samani, A Jalili, A Bahrampour, R Maddah - Informatics in Medicine …, 2023 - Elsevier
Objective Hepatocellular carcinoma (HCC) is a malignancy showing rising prevalence and
mortality rates despite scientific progress. Studies indicate that Epithelial-Mesenchymal …

[PDF][PDF] BBA-Molecular Basis of Disease

Y Chen, L Yu, Y Wang, Y Wei, Y Xu, T He, R He - 2016 - researchgate.net
In humans, more than 200 missense mutations have been identified in the ACTA1 gene. The
exact molecular mechanisms by which, these particular mutations become toxic and lead to …