Recent innovations in bacterial infection detection and treatment

C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …

Narrow-spectrum antibacterial agents

RJ Melander, DV Zurawski, C Melander - Medchemcomm, 2018 - pubs.rsc.org
While broad spectrum antibiotics play an invaluable role in the treatment of bacterial
infections, there are some drawbacks to their use, namely selection for and spread of …

Prevention of dental caries as a non‐communicable disease

S Twetman - European journal of oral sciences, 2018 - Wiley Online Library
Today, dental caries is regarded as a preventable non‐communicable disease (NCD) that
affects a majority of the population across their lifespan. As such, it shares a number of …

Oral microbiota and Alzheimer's disease: Do all roads lead to Rome?

A Sureda, M Daglia, SA Castilla, N Sanadgol… - Pharmacological …, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative pathology affecting milions of
people worldwide associated with deposition of senile plaques. While the genetic and …

The current strategies in controlling oral diseases by herbal and chemical materials

MN Motallaei, M Yazdanian… - Evidence‐Based …, 2021 - Wiley Online Library
Dental plaque is a biofilm composed of complex microbial communities. It is the main cause
of major dental diseases such as caries and periodontal diseases. In a healthy state, there is …

Antimicrobial host defence peptides: immunomodulatory functions and translational prospects

AM van der Does, PS Hiemstra… - … Peptides: Basics for …, 2019 - Springer
Cationic host defence peptides (CHDPs), also known as antimicrobial peptides, exhibit a
wide range of activities contributing to immune responses and resolution of infections …

Targeted and Intracellular Antibacterial Activity against S. agalactiae of the Chimeric Peptides Based on Pheromone and Cell-Penetrating Peptides

J Li, L Shang, J Lan, S Chou, X Feng… - … Applied Materials & …, 2020 - ACS Publications
The significance of the complex bacterial ecosystem in the human body and the impediment
of the mammalian membrane against many antibiotics together emphasize the necessity to …

Three innovations of next-generation antibiotics: evolvability, specificity, and non-immunogenicity

H Shim - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance is a silent pandemic exacerbated by the uncontrolled use of
antibiotics. Since the discovery of penicillin, we have been largely dependent on microbe …

Gram-selective antibacterial peptide hydrogels

Y Hou, T Tan, Z Guo, Y Ji, J Hu, Y Zhang - Biomaterials Science, 2022 - pubs.rsc.org
The human microbiome plays fundamental roles in human health and disease. However,
widely used broad-spectrum antibiotics severely disrupt human-related microbial …

Effect of a Short-Term Intervention with Lactobacillus salivarius Probiotic on Early Childhood Caries—An Open Label Randomized Controlled Trial

M Staszczyk, M Jamka-Kasprzyk, D Kościelniak… - International Journal of …, 2022 - mdpi.com
ECC is a significant therapeutic and social problem and a global burden on public health.
The aim of this clinical trial was to test whether a 2-week daily consumption of chewing …