The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Neurobiology of addiction: a neurocircuitry analysis

GF Koob, ND Volkow - The Lancet Psychiatry, 2016 - thelancet.com
Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by
a combination of exaggerated incentive salience and habit formation, reward deficits and …

The oxytocin receptor system: structure, function, and regulation

G Gimpl, F Fahrenholz - Physiological reviews, 2001 - journals.physiology.org
The neurohypophysial peptide oxytocin (OT) and OT-like hormones facilitate reproduction in
all vertebrates at several levels. The major site of OT gene expression is the magnocellular …

Neuroendocrine perspectives on social attachment and love

CS Carter - Psychoneuroendocrinology, 1998 - Elsevier
The purpose of this paper is to review existing behavioral and neuroendocrine perspectives
on social attachment and love. Both love and social attachments function to facilitate …

A neurobehavioral model of affiliative bonding: Implications for conceptualizing a human trait of affiliation

RA Depue, JV Morrone-Strupinsky - Behavioral and Brain Sciences, 2005 - cambridge.org
primate research suggests that affiliation is a highly complex construct. studies of primate
affiliation demonstrate the need to distinguish between various affiliative behaviors, consider …

Lust, attraction, and attachment in mammalian reproduction

HE Fisher - Human nature, 1998 - Springer
This paper proposes that mammals exhibit three primary emotion categories for mating and
reproduction:(1) the sex drive, or lust, characterized by the craving for sexual gratification;(2) …

Physiological substrates of mammalian monogamy: the prairie vole model

CS Carter, AC Devries, LL Getz - Neuroscience & Biobehavioral Reviews, 1995 - Elsevier
Prairie voles (Microtus ochrogaster) are described here as a model system in which it is
possible to examine, within the context of natural history, the proximate processes regulating …

Dopamine and oxytocin interactions underlying behaviors: potential contributions to behavioral disorders

TA Baskerville, AJ Douglas - CNS neuroscience & therapeutics, 2010 - Wiley Online Library
Dopamine is an important neuromodulator that exerts widespread effects on the central
nervous system (CNS) function. Disruption in dopaminergic neurotransmission can have …

Nucleus accumbens oxytocin and dopamine interact to regulate pair bond formation in female prairie voles

Y Liu, ZX Wang - Neuroscience, 2003 - Elsevier
Although oxytocin (OT) and dopamine (DA) have been implicated in pair bond formation in
monogamous prairie voles (Microtus ochrogaster), the nature of potential interactions …

Is social attachment an addictive disorder?

TR Insel - Physiology & behavior, 2003 - Elsevier
There is a considerable literature on the neurobiology of reward, based largely on studies of
addiction or substance abuse. This review considers the possibility that the neural circuits …