Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

F Kronenberg, S Mora, ESG Stroes… - European heart …, 2022 - academic.oup.com
Abstract This 2022 European Atherosclerosis Society lipoprotein (a)[Lp (a)] consensus
statement updates evidence for the role of Lp (a) in atherosclerotic cardiovascular disease …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

[HTML][HTML] Multiomics study of nonalcoholic fatty liver disease

G Sveinbjornsson, MO Ulfarsson, RB Thorolfsdottir… - Nature …, 2022 - nature.com
Nonalcoholic fatty liver (NAFL) and its sequelae are growing health problems. We performed
a genome-wide association study of NAFL, cirrhosis and hepatocellular carcinoma, and …

Lipid and lipoprotein metabolism

KR Feingold - Endocrinology and Metabolism Clinics, 2022 - endo.theclinics.com
Lipids are insoluble in water and therefore cholesterol and triglycerides need to be
transported in association with proteins (ie, lipoproteins) in the bloodstream. Lipoproteins …

[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene

S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …

Effect of pelacarsen on lipoprotein (a) cholesterol and corrected low-density lipoprotein cholesterol

C Yeang, E Karwatowska-Prokopczuk, F Su… - Journal of the American …, 2022 - jacc.org
Background Laboratory methods that report low-density lipoprotein cholesterol (LDL-C)
include both LDL-C and lipoprotein (a) cholesterol [Lp (a)-C] content. Objectives The …

Lipoprotein (a): Knowns, unknowns and uncertainties

M Ruscica, CR Sirtori, A Corsini, GF Watts… - Pharmacological …, 2021 - Elsevier
Over the last 10 years, there have been advances on several aspects of lipoprotein (a)
which are reviewed in the present article. Since the standard immunoassays for measuring …

Oxidized phospholipids in cardiovascular disease

S Tsimikas, JL Witztum - Nature Reviews Cardiology, 2024 - nature.com
Prolonged or excessive exposure to oxidized phospholipids (OxPLs) generates chronic
inflammation. OxPLs are present in atherosclerotic lesions and can be detected in plasma …

[HTML][HTML] Calcific aortic stenosis—a review on acquired mechanisms of the disease and treatments

B Zebhi, M Lazkani, D Bark Jr - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Calcific aortic stenosis is a progressive disease that has become more prevalent in recent
decades. Despite advances in research to uncover underlying biomechanisms, and …

Elevated lipoprotein (a): background, current insights and future potential therapies

A Handhle, A Viljoen, AS Wierzbicki - Vascular Health and Risk …, 2021 - Taylor & Francis
Lipoprotein (a) forms a subfraction of the lipid profile and is characterized by the addition of
apolipprotein (a)(apo (a)) to apoB100 derived particles. Its levels are mostly genetically …