Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics …

D Astruc, E Boisselier, C Ornelas - Chemical reviews, 2010 - ACS Publications
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …

Nanomaterials: applications in cancer imaging and therapy

JA Barreto, W O'Malley, M Kubeil, B Graham… - Advanced …, 2011 - Wiley Online Library
The application of nanomaterials (NMs) in biomedicine is increasing rapidly and offers
excellent prospects for the development of new non‐invasive strategies for the diagnosis …

Gadolinium‐based contrast agents for magnetic resonance cancer imaging

Z Zhou, ZR Lu - Wiley Interdisciplinary Reviews: Nanomedicine …, 2013 - Wiley Online Library
Magnetic resonance imaging (MRI) is a clinical imaging modality effective for anatomical
and functional imaging of diseased soft tissues, including solid tumors. MRI contrast agents …

Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

AJL Villaraza, A Bumb, MW Brechbiel - Chemical reviews, 2010 - ACS Publications
Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

Emerging nanopharmaceuticals

WE Bawarski, E Chidlowsky, DJ Bharali… - … , Biology and Medicine, 2008 - Elsevier
A budding interest in nanopharmaceuticals has generated a number of advancements
throughout recent years with a focus on engineering novel applications. Nanotechnology …

Gadolinium (III) complexes as MRI contrast agents: ligand design and properties of the complexes

P Hermann, J Kotek, V Kubíček, I Lukeš - Dalton Transactions, 2008 - pubs.rsc.org
Magnetic resonance imaging is a commonly used diagnostic method in medicinal practice
as well as in biological and preclinical research. Contrast agents (CAs), which are often …

Combinatorial chemistry identifies high-affinity peptidomimetics against α4β1 integrin for in vivo tumor imaging

L Peng, R Liu, J Marik, X Wang, Y Takada… - Nature chemical …, 2006 - nature.com
Small peptide–based agents have attracted wide interest as cancer-targeting agents for
diagnostic imaging and targeted therapy. There is a need to develop new high-affinity and …

Dendrimer-based nanoprobe for dual modality magnetic resonance and fluorescence imaging

VS Talanov, CAS Regino, H Kobayashi, M Bernardo… - Nano …, 2006 - ACS Publications
A novel PAMAM dendrimer-based nanoprobe for dual magnetic resonance and
fluorescence imaging modalities was synthesized. Fluorescence studies revealed that Gd …

Natural and synthetic polymers as inhibitors of drug efflux pumps

M Werle - Pharmaceutical Research, 2008 - Springer
Inhibition of efflux pumps is an emerging approach in cancer therapy and drug delivery.
Since it has been discovered that polymeric pharmaceutical excipients such as Tweens® or …