A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

The neurobiological mechanisms underlying prefrontal transcranial direct current stimulation
(tDCS) remain elusive. Randomized, sham-controlled trials in humans and rodents applying …

Substance use problems impair social functioning, academic achievement, and
employability. Psychological, biological, social, and environmental factors can contribute to …

Neuroimaging studies in substance use disorder have shown widespread impairments in
white matter (WM) microstructure suggesting demyelination and axonal damage. However …

Background: The fornix is the primary axonal tract of the hippocampus, connecting it to
modulatory subcortical structures. This review reveals that fornix damage causes cognitive …

Individuals suffering from chronic pain develop substance use disorders (SUDs) more often
than others. Understanding the shared genetic influences underlying the comorbidity …

Oligodendrocyte progenitor cells (OPCs) receive synaptic innervation from glutamatergic
and GABAergic axons and can be dynamically regulated by neural activity, resulting in …

Introduction: Besides the commonly described gray matter (GM) deficits, there is growing
evidence of significant white matter (WM) alterations in patients with alcohol use disorder …

Diffusion tractography allows identification and measurement of structural tracts in the
human brain previously associated with motivated behavior in animal models. Recent …

Detection of microstructural white matter injury in traumatic brain injury (TBI) requires
specialised imaging methods, of which diffusion tensor imaging (DTI) has been extensively …