Purpose The aims of this article were to systematically review the literature about the
mechanism of action of colchicine in the multimodal pathology of acute inflammation …

A n D GUID eLIneS affordability may often dictate which medications may be prescribed.
Patients who have exhausted prescription drug coverage or who are uninsured may require …

Although colchicine has been a focus of research, debate, and controversy for thousands of
years, the US Food and Drug Administration just approved it in 2009. Over the past decade …

Introduction. Colchicine is used mainly for the treatment and prevention of gout and for
familial Mediterranean fever (FMF). It has a narrow therapeutic index, with no clear-cut …

HMG-CoA reductase inhibitors (statins) are a widely used class of drug, and like all
medications, have potential for adverse effects (AEs). Here we review the statin AE literature …

OBJECTIVES: To review recent advances in the understanding of molecular mechanisms of
drug disposition and cellular mechanisms of action and targets of colchicine, and disease …

Colchicine (COL) has been used in medicine for a long time. It is well recognized as a valid
therapy in acute flares of gouty arthritis, familial Mediterranean fever (FMF), Behçet's …

Drugs are prescribed to manage or prevent symptoms and diseases, but may sometimes
cause unexpected toxicity to muscles. The symptomatology and clinical manifestations of the …

The paper addresses the safety of febuxostat and summarizes reports on side effects and
interactions of febuxostat published by the cut-off date (last day of literature search) of 20 …

Colchicine has been effectively used in the treatment of several inflammatory conditions,
such as gouty attacks, serositis related to familial Mediterranean fever, Behçet syndrome …