Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Heating technology for malignant tumors: A review

HP Kok, ENK Cressman, W Ceelen… - International Journal …, 2020 - Taylor & Francis
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia,
ie, heating to 39–45° C to induce sensitization to radiotherapy and chemotherapy, and …

Pangolin-inspired untethered magnetic robot for on-demand biomedical heating applications

RH Soon, Z Yin, MA Dogan, NO Dogan… - Nature …, 2023 - nature.com
Untethered magnetic miniature soft robots capable of accessing hard-to-reach regions can
enable safe, disruptive, and minimally invasive medical procedures. However, the soft body …

Immunomodulation and targeted drug delivery with high intensity focused ultrasound (HIFU): Principles and mechanisms

H Ashar, A Ranjan - Pharmacology & Therapeutics, 2023 - Elsevier
High intensity focused ultrasound (HIFU) is a non-invasive and non-ionizing sonic energy-
based therapeutic technology for inducing thermal and non-thermal effects in tissues …

Bioorthogonal chemistry for prodrug activation in vivo

Q Fu, S Shen, P Sun, Z Gu, Y Bai, X Wang… - Chemical Society …, 2023 - pubs.rsc.org
Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

Principles and applications of sono-optogenetics

F Yang, SJ Kim, X Wu, H Cui, SK Hahn… - Advanced Drug Delivery …, 2023 - Elsevier
Optogenetics has revolutionized neuroscience research through its spatiotemporally precise
activation of specific neurons by illuminating light on opsin-expressing neurons. A long …

Recent advancements in electroporation technologies: from bench to clinic

SN Campelo, PH Huang, CR Buie… - Annual Review of …, 2023 - annualreviews.org
Over the past decade, the increased adoption of electroporation-based technologies has led
to an expansion of clinical research initiatives. Electroporation has been utilized in …

Phase-shift nanodroplets as an emerging sonoresponsive nanomaterial for imaging and drug delivery applications

W Zhang, Y Shi, S Abd Shukor, A Vijayakumaran… - Nanoscale, 2022 - pubs.rsc.org
Nanodroplets–emerging phase-changing sonoresponsive materials–have attracted
substantial attention in biomedical applications for both tumour imaging and therapeutic …

[HTML][HTML] Smart magnetic resonance imaging-based theranostics for cancer

B Brito, TW Price, J Gallo, M Bañobre-López… - Theranostics, 2021 - ncbi.nlm.nih.gov
Smart theranostics are dynamic platforms that integrate multiple functions, including at least
imaging, therapy, and responsiveness, in a single agent. This review showcases a variety of …

Fast volumetric ultrasound facilitates high-resolution 3D mapping of tissue compartments

EY Park, X Cai, J Foiret, H Bendjador, D Hyun… - Science …, 2023 - science.org
Volumetric ultrasound imaging has the potential for operator-independent acquisition and
enhanced field of view. Panoramic acquisition has many applications across ultrasound; …