What is wrong with pertussis vaccine immunity? The problem of waning effectiveness of pertussis vaccines

N Burdin, LK Handy, SA Plotkin - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Pertussis is resurgent in some countries, particularly those in which children receive
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …

Bordetella pertussis

DJ Nieves, U Heininger - Emerging Infections 10, 2016 - Wiley Online Library
Pertussis is a highly contagious acute respiratory illness classically known as “whooping
cough” because of its characteristic cough. The majority of cases are caused by Bordetella …

[HTML][HTML] Prevention of pertussis, tetanus, and diphtheria with vaccines in the United States: recommendations of the Advisory Committee on Immunization Practices …

JL Liang - MMWR. Recommendations and reports, 2018 - cdc.gov
This report compiles and summarizes all recommendations from CDC's Advisory Committee
on Immunization Practices (ACIP) regarding prevention and control of tetanus, diphtheria …

[HTML][HTML] Use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccines: updated recommendations of the Advisory Committee on Immunization …

FP Havers - MMWR. Morbidity and mortality weekly report, 2020 - cdc.gov
Background Two Tdap vaccines are licensed for use in the United States. Boostrix
(GlaxoSmithKline) is approved for a single dose in persons aged≥ 10 years; Adacel (Sanofi …

Pertussis (whooping cough)

MD Decker, KM Edwards - The Journal of Infectious Diseases, 2021 - academic.oup.com
Pertussis (whooping cough) is a respiratory infection caused by Bordetella pertussis. All
ages are susceptible. In the prevaccine era, almost all children became infected. Pertussis is …

The epidemiology of nationally reported pertussis in the United States, 2000–2016

TH Skoff, S Hadler, S Hariri - Clinical Infectious Diseases, 2019 - academic.oup.com
Background Despite successful vaccination programs, pertussis remains endemic in the
United States, and increasing incidence has been reported. We used national surveillance …

Waning Tdap effectiveness in adolescents

NP Klein, J Bartlett, B Fireman, R Baxter - Pediatrics, 2016 - publications.aap.org
METHODS: We modeled pertussis risk in relation to Tdap vaccination status among
adolescents beginning on their 10th birthday. We estimated the hazard ratio (HR) for each …

Exploring childhood vaccination themes and public opinions on Twitter: A semantic network analysis

JD Featherstone, JB Ruiz, GA Barnett… - Telematics and Informatics, 2020 - Elsevier
During the summer of 2018, a measles outbreak hit Europe, resulting in infections and
deaths. Reports link the outbreak to increasing vaccine hesitancy fueled partly by anti …

The 112-year odyssey of pertussis and pertussis vaccines—mistakes made and implications for the future

JD Cherry - Journal of the Pediatric Infectious Diseases Society, 2019 - academic.oup.com
Effective diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines became
available in the 1930s, and they were put into routine use in the United States in the 1940s …

Successful vaccines

IJ Amanna, MK Slifka - Vaccination strategies against highly variable …, 2020 - Springer
Vaccines are considered one of the most important advances in modern medicine and have
greatly improved our quality of life by reducing or eliminating many serious infectious …