When the central integrator disintegrates: A review of the role of the thalamus in cognition and dementia

JM Biesbroek, MG Verhagen… - Alzheimer's & …, 2024 - Wiley Online Library
The thalamus is a complex neural structure with numerous anatomical subdivisions and
intricate connectivity patterns. In recent decades, the traditional view of the thalamus as a …

[HTML][HTML] Intermittent metabolic switching and vascular cognitive impairment

V Rajeev, NI Tabassum, DY Fann… - Journal of Obesity & …, 2024 - ncbi.nlm.nih.gov
Intermittent fasting (IF), a dietary pattern alternating between eating and fasting periods
within a 24-hour cycle, has garnered recognition for its potential to enhance both healthspan …

[HTML][HTML] White matter hyperintensity volume and poststroke cognition: an individual patient data pooled analysis of 9 ischemic stroke cohort studies

FAS De Kort, M Coenen, NA Weaver, HJ Kuijf… - Stroke, 2023 - journals.lww.com
BACKGROUND: White matter hyperintensities (WMH) are associated with cognitive
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …

Regional cortical thinning, demyelination and iron loss in cerebral small vessel disease

H Li, MA Jacob, M Cai, M Duering, M Chamberland… - Brain, 2023 - academic.oup.com
The link between white matter hyperintensities (WMH) and cortical thinning is thought to be
an important pathway by which WMH contributes to cognitive deficits in cerebral small …

Advances in Stroke: Brain Health in 2023

T Rundek, CLH Chen - Stroke, 2023 - Am Heart Assoc
The best solution continues to be prevention and preservation of brain health. Brain health is
defined as “optimal capacity to function adaptively in the environment” by the American …

[HTML][HTML] White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition

D Bachmann, B von Rickenbach, A Buchmann… - Alzheimer's Research & …, 2024 - Springer
Abstract Background White matter hyperintensities (WMHs) are often measured globally, but
spatial patterns of WMHs could underlie different risk factors and neuropathological and …

[HTML][HTML] Can white matter hyperintensities based Fazekas visual assessment scales inform about Alzheimer's disease pathology in the population?

A Pradeep, S Raghavan, SA Przybelski… - Alzheimer's Research & …, 2024 - Springer
Background White matter hyperintensities (WMH) are considered hallmark features of
cerebral small vessel disease and have recently been linked to Alzheimer's disease (AD) …

[HTML][HTML] Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts

M Coenen, GJ Biessels, C DeCarli, EF Fletcher… - NeuroImage: Clinical, 2023 - Elsevier
Introduction The spatial distribution of white matter hyperintensities (WMH) on MRI is often
considered in the diagnostic evaluation of patients with cognitive problems. In some …

[HTML][HTML] National and international collaborations to advance research into vascular contributions to cognitive decline

DG Saks, EE Smith, PS Sachdev - Cerebral Circulation-Cognition and …, 2024 - Elsevier
Cerebrovascular disease is the second most common cause of cognitive disorders, usually
referred to as vascular contributions to cognitive impairment and dementia (VCID) and …

The genetic and environmental etiology of novel frequency‐driven regional parcellations of abnormal white matter

SJ Lin, NA Gillespie, R Notestine… - American Journal of …, 2024 - Wiley Online Library
The prevalence of white matter disease increases with age and is associated with
cerebrovascular disease, cognitive decline, and risk for dementia. MRI measures of …