When the central integrator disintegrates: A review of the role of the thalamus in cognition and dementia
JM Biesbroek, MG Verhagen… - Alzheimer's & …, 2024 - Wiley Online Library
The thalamus is a complex neural structure with numerous anatomical subdivisions and
intricate connectivity patterns. In recent decades, the traditional view of the thalamus as a …
intricate connectivity patterns. In recent decades, the traditional view of the thalamus as a …
[HTML][HTML] Intermittent metabolic switching and vascular cognitive impairment
V Rajeev, NI Tabassum, DY Fann… - Journal of Obesity & …, 2024 - ncbi.nlm.nih.gov
Intermittent fasting (IF), a dietary pattern alternating between eating and fasting periods
within a 24-hour cycle, has garnered recognition for its potential to enhance both healthspan …
within a 24-hour cycle, has garnered recognition for its potential to enhance both healthspan …
[HTML][HTML] White matter hyperintensity volume and poststroke cognition: an individual patient data pooled analysis of 9 ischemic stroke cohort studies
BACKGROUND: White matter hyperintensities (WMH) are associated with cognitive
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …
Regional cortical thinning, demyelination and iron loss in cerebral small vessel disease
The link between white matter hyperintensities (WMH) and cortical thinning is thought to be
an important pathway by which WMH contributes to cognitive deficits in cerebral small …
an important pathway by which WMH contributes to cognitive deficits in cerebral small …
Advances in Stroke: Brain Health in 2023
T Rundek, CLH Chen - Stroke, 2023 - Am Heart Assoc
The best solution continues to be prevention and preservation of brain health. Brain health is
defined as “optimal capacity to function adaptively in the environment” by the American …
defined as “optimal capacity to function adaptively in the environment” by the American …
[HTML][HTML] White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition
D Bachmann, B von Rickenbach, A Buchmann… - Alzheimer's Research & …, 2024 - Springer
Abstract Background White matter hyperintensities (WMHs) are often measured globally, but
spatial patterns of WMHs could underlie different risk factors and neuropathological and …
spatial patterns of WMHs could underlie different risk factors and neuropathological and …
[HTML][HTML] Can white matter hyperintensities based Fazekas visual assessment scales inform about Alzheimer's disease pathology in the population?
A Pradeep, S Raghavan, SA Przybelski… - Alzheimer's Research & …, 2024 - Springer
Background White matter hyperintensities (WMH) are considered hallmark features of
cerebral small vessel disease and have recently been linked to Alzheimer's disease (AD) …
cerebral small vessel disease and have recently been linked to Alzheimer's disease (AD) …
[HTML][HTML] Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts
Introduction The spatial distribution of white matter hyperintensities (WMH) on MRI is often
considered in the diagnostic evaluation of patients with cognitive problems. In some …
considered in the diagnostic evaluation of patients with cognitive problems. In some …
[HTML][HTML] National and international collaborations to advance research into vascular contributions to cognitive decline
Cerebrovascular disease is the second most common cause of cognitive disorders, usually
referred to as vascular contributions to cognitive impairment and dementia (VCID) and …
referred to as vascular contributions to cognitive impairment and dementia (VCID) and …
The genetic and environmental etiology of novel frequency‐driven regional parcellations of abnormal white matter
SJ Lin, NA Gillespie, R Notestine… - American Journal of …, 2024 - Wiley Online Library
The prevalence of white matter disease increases with age and is associated with
cerebrovascular disease, cognitive decline, and risk for dementia. MRI measures of …
cerebrovascular disease, cognitive decline, and risk for dementia. MRI measures of …