Apoptosis: target of cancer therapy

CG Ferreira, M Epping, FAE Kruyt, G Giaccone - Clinical Cancer Research, 2002 - AACR
Recent knowledge on apoptosis has made it possible to devise novel approaches, which
exploit this process to treat cancer. In this review, we discuss in detail approaches to induce …

Subcellular targets of cisplatin cytotoxicity: an integrated view

SM Sancho-Martínez, L Prieto-García, M Prieto… - Pharmacology & …, 2012 - Elsevier
Cisplatin is a chemotherapeutic drug widely used against a variety of cancers. Its clinical
utility is severely limited by its toxicity, which mainly affects, but is not limited to, the inner ear …

Stimulation of glutathione depletion, ROS production and cell cycle arrest of dental pulp cells and gingival epithelial cells by HEMA

HH Chang, MK Guo, FH Kasten, MC Chang, GF Huang… - Biomaterials, 2005 - Elsevier
2-Hydroxy-ethyl methacrylate (HEMA) is the major component released from resin-modified
glass ionomer cements and dental adhesives. Human tissues mainly affected by HEMA are …

[图书][B] Molecular biology of cancer

F Macdonald, C Ford, A Casson - 2004 - taylorfrancis.com
Molecular Biology of Cancer has been extensively revised and covers heredity cancer,
microarray technology and increased study of childhood cancers. It continues to provide a …

Areca nut extract and arecoline induced the cell cycle arrest but not apoptosis of cultured oral KB epithelial cells: association of glutathione, reactive oxygen species …

MC Chang, YS Ho, PH Lee, CP Chan, JJ Lee… - …, 2001 - academic.oup.com
There are 600 million betel quid (BQ) chewers in the world. BQ chewing is a major etiologic
factor of oral cancer. Areca nut (AN) and arecoline may inhibit the growth of oral mucosal …

Combinational effect of curcumin and metformin against gentamicin‐induced nephrotoxicity: Involvement of antioxidative, anti‐inflammatory and antiapoptotic pathway

L Cao, D Zhi, J Han, S Kumar Sah… - Journal of food …, 2019 - Wiley Online Library
Gentamicin (GM) is an antibiotic related to aminoglycoside group that is used in treating
Gram‐negative bacterial infections. However, treatment with gentamicin is considered to be …

Receptor-and mitochondrial-mediated apoptosis in acute leukemia: a translational view

AD Schimmer, DW Hedley, LZ Penn… - Blood, The Journal of …, 2001 - ashpublications.org
Acute myeloid leukemia and adult-onset acute lymphocytic leukemia are aggressive
diseases with generally poor prognoses. The primary cause of treatment failures in patients …

10‐HDA Induces ROS‐Mediated Apoptosis in A549 Human Lung Cancer Cells by Regulating the MAPK, STAT3, NF‐κB, and TGF‐β1 Signaling Pathways

XM Lin, SB Liu, YH Luo, WT Xu, Y Zhang… - BioMed Research …, 2020 - Wiley Online Library
10‐Hydroxy‐2‐decenoic acid (10‐HDA), also known as royal jelly acid, has a variety of
physiological functions, and recent studies have shown that it also has anticancer effects …

Emodin induces apoptosis through caspase 3-dependent pathway in HK-2 cells

C Wang, X Wu, M Chen, W Duan, L Sun, M Yan… - Toxicology, 2007 - Elsevier
Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is a major constituent of rhubarb.
Although it has been claimed to have a wild spectrum of therapeutic value, its side effects …

[HTML][HTML] Exosomes and other extracellular vesicles in HPV transmission and carcinogenesis

D Guenat, F Hermetet, JL Prétet, C Mougin - Viruses, 2017 - mdpi.com
Extracellular vesicles (EVs), including exosomes (Exos), microvesicles (MVs) and apoptotic
bodies (ABs) are released in biofluids by virtually all living cells. Tumor-derived Exos and …