This review focuses on the use of angiotensin converting enzyme (ACE) inhibitors in
hypertensive diseases. Specifically discussed are: proposed mechanisms of action, the …

• The effect of low doses (25 mg three times a day) of captopril was evaluated in 16 patients
with mild to moderate essential hypertension, previously uncontrolled by …

The antihypertensive efficacy of a combination of calcium-channel blockers and angiotensin-
converting-enzyme (ACE) inhibitors in severe primary hypertension is well known, but a …

1 Forty‐one patients with primary (essential) hypertension were treated with captopril alone
or in combination with hydrochlorothiazide for 12‐36 months. 2 During an initial dose …

1 Fifty‐seven patients with mild or moderate essential hypertension, mean age 50 (range 31‐
69) were randomised to treatment with either captopril or atenolol. Twenty‐six patients in …

Seventy‐four patients from four short‐term studies of captopril in mild‐moderate essential
hypertension continued in a cooperative long‐term efficacy and tolerance program. The …

Abstract The immediate (0 to 24 hours) and long-term (4 weeks) hypotensive effects of a
new long-acting angiotensin converting enzyme inhibitor, ramipril (HOE 498), as well as …

Fifty patients with mild or moderate essential hypertension were randomized (double‐
blindly) to treatment with either captopril (n= 26) or atenolol (n= 24). Their mean supine …

The antihypertensive effect of enalapril maleate, a new converting enzyme inhibitor, was
evaluated in a multiclinic, double-blind, randomized study in patients with mild to moderate …

The effects of captopril (SQ 14.225), an orally active inhibitor of angiotensin converting
enzyme, were investigated in a dose titration study of primary hypertension. In 32 patients 4 …