Sialic acids in human health and disease
A Varki - Trends in molecular medicine, 2008 - cell.com
The surfaces of all vertebrate cells are decorated with a dense and complex array of sugar
chains, which are mostly attached to proteins and lipids. Most soluble secreted proteins are …
chains, which are mostly attached to proteins and lipids. Most soluble secreted proteins are …
Oligosaccharide specificity of galectins: a search by frontal affinity chromatography
J Hirabayashi, T Hashidate, Y Arata, N Nishi… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Galectins are widely distributed sugar-binding proteins whose basic specificity for β-
galactosides is conserved by evolutionarily preserved carbohydrate-recognition domains …
galactosides is conserved by evolutionarily preserved carbohydrate-recognition domains …
[HTML][HTML] Applications of nanobiomaterials in the therapy and imaging of acute liver failure
Highlights This review focuses on the therapeutic mechanisms, targeting strategies of
various nanomaterials in acute liver failure, and recent advances of diverse nanomaterials …
various nanomaterials in acute liver failure, and recent advances of diverse nanomaterials …
From lectin structure to functional glycomics: principles of the sugar code
HJ Gabius, S André, J Jiménez-Barbero… - Trends in biochemical …, 2011 - cell.com
Lectins are carbohydrate-binding proteins which lack enzymatic activity on their ligand and
are distinct from antibodies and free mono-and oligosaccharide sensor/transport proteins …
are distinct from antibodies and free mono-and oligosaccharide sensor/transport proteins …
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
RJ Solá, K Griebenow - BioDrugs, 2010 - Springer
During their development and administration, protein-based drugs routinely display
suboptimal therapeutic efficacies due to their poor physicochemical and pharmacological …
suboptimal therapeutic efficacies due to their poor physicochemical and pharmacological …
Pectin in cancer therapy: A review
W Zhang, P Xu, H Zhang - Trends in Food Science & Technology, 2015 - Elsevier
Highlights•Overview of the application and anti-cancer mechanisms of dietary
pectin.•Structure-activity relationships of modified pectin are discussed.•Anti-cancer …
pectin.•Structure-activity relationships of modified pectin are discussed.•Anti-cancer …
The mannose receptor family
L East, CM Isacke - Biochimica et Biophysica Acta (BBA)-General Subjects, 2002 - Elsevier
The mannose receptor family comprises four glycoproteins each of which is a type I
transmembrane receptor with an N-terminal cysteine-rich domain, a single fibronectin type II …
transmembrane receptor with an N-terminal cysteine-rich domain, a single fibronectin type II …
Chondroitin sulphate: a focus on osteoarthritis
Chondroitin sulfate (CS) being a natural glycosaminoglycan is found in the cartilage and
extracellular matrix. It shows clinical benefits in symptomatic osteoarthritis (OA) of the finger …
extracellular matrix. It shows clinical benefits in symptomatic osteoarthritis (OA) of the finger …
Prodrug strategies in anticancer chemotherapy
F Kratz, IA Müller, C Ryppa… - … Chemistry Enabling Drug …, 2008 - Wiley Online Library
The majority of clinically approved anticancer drugs are characterized by a narrow
therapeutic window that results mainly from a high systemic toxicity of the drugs in …
therapeutic window that results mainly from a high systemic toxicity of the drugs in …
Chemical biology of the sugar code
HJ Gabius, HC Siebert, S André… - …, 2004 - Wiley Online Library
A high‐density coding system is essential to allow cells to communicate efficiently and
swiftly through complex surface interactions. All the structural requirements for forming a …
swiftly through complex surface interactions. All the structural requirements for forming a …