Roles of transposable elements in the regulation of mammalian transcription
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …
contain sequences capable of recruiting the host transcription machinery, which they use to …
Cis-regulatory sequences in plants: their importance, discovery, and future challenges
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …
function to coordinate responses to developmental and environmental cues is of paramount …
Origins and evolutionary consequences of ancient endogenous retroviruses
WE Johnson - Nature Reviews Microbiology, 2019 - nature.com
Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …
Mammalian genome innovation through transposon domestication
Since the discovery of transposons, their sheer abundance in host genomes has puzzled
many. While historically viewed as largely harmless 'parasitic'DNAs during evolution …
many. While historically viewed as largely harmless 'parasitic'DNAs during evolution …
Transposable elements as essential elements in the control of gene expression
A Gebrie - Mobile DNA, 2023 - Springer
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …
Transposable elements as a potent source of diverse cis-regulatory sequences in mammalian genomes
V Sundaram, J Wysocka - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
Eukaryotic gene regulation is mediated by cis-regulatory elements, which are embedded
within the vast non-coding genomic space and recognized by the transcription factors in a …
within the vast non-coding genomic space and recognized by the transcription factors in a …
The epigenomic landscape of transposable elements across normal human development and anatomy
EC Pehrsson, MNK Choudhary, V Sundaram… - Nature …, 2019 - nature.com
Transposable elements (TEs) have deposited functional regulatory elements throughout the
human genome. Although most are silenced, certain TEs have been co-opted by the host …
human genome. Although most are silenced, certain TEs have been co-opted by the host …
[HTML][HTML] Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells
The majority of mammalian genomes are devoted to transposable elements (TEs). Whilst
TEs are increasingly recognized for their important biological functions, they are a potential …
TEs are increasingly recognized for their important biological functions, they are a potential …
Evolutionary rewiring of the wheat transcriptional regulatory network by lineage-specific transposable elements
Y Zhang, Z Li, K Lin, Y Peng, L Ye, Y Zhuang… - Genome …, 2021 - genome.cshlp.org
More than 80% of the wheat genome consists of transposable elements (TEs), which act as
major drivers of wheat genome evolution. However, their contributions to the regulatory …
major drivers of wheat genome evolution. However, their contributions to the regulatory …
[HTML][HTML] The placenta goes viral: Retroviruses control gene expression in pregnancy
EB Chuong - PLoS biology, 2018 - journals.plos.org
The co-option of endogenous retroviruses (ERVs) is increasingly recognized as a recurrent
theme in placental biology, which has far-reaching implications for our understanding of …
theme in placental biology, which has far-reaching implications for our understanding of …