Importance Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory
disease of the esophagus that affects an estimated 34.4/100 000 people in Europe and …

Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …

Background Eosinophilic oesophagitis (EoE) is an increasingly common cause of dysphagia
in both children and adults, as well as one of the most prevalent oesophageal diseases with …

Background & Aims Disease activity and severity of eosinophilic esophagitis (EoE) dictate
therapeutic options and management, but the decision-making process for determining …

Background & Aims Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder.
Swallowed topical-acting corticosteroids are effective in bringing active EoE into remission …

Objective We aimed to determine whether mepolizumab, an anti-IL-5 antibody, was more
effective than placebo for improving dysphagia symptoms and decreasing oesophageal …

Background End points used to determine treatment efficacy in eosinophilic esophagitis
(EoE) have evolved over time. With multiple novel therapies in development for EoE …

In the absence of secondary causes, eosinophilic esophagitis (EoE) is a chronic, local,
progressive, T-helper type 2 immune-mediated disorder characterized by symptoms of …

Background There is currently no recommendation regarding preferred drugs for active
eosinophilic oesophagitis (EoE) because their relative efficacy is unclear. We conducted an …

Eosinophilic esophagitis (EoE) is an increasingly common inflammatory allergic disease of
the esophagus characterized by esophageal eosinophilia and symptoms of esophageal …