[HTML][HTML] Acquired brain injuries across the perinatal spectrum: Pathophysiology and emerging therapies

JB Russ, BEL Ostrem - Pediatric neurology, 2023 - Elsevier
The development of the central nervous system can be directly disrupted by a variety of
acquired factors, including infectious, inflammatory, hypoxic-ischemic, and toxic insults …

[HTML][HTML] The role of lymphocytes in neonatal encephalopathy

AM Melo, NAB Taher, DG Doherty, EJ Molloy - Brain, Behavior, & Immunity …, 2021 - Elsevier
Neonatal encephalopathy is a syndrome characterised by abnormal neurological function
often caused by a hypoxic insult during childbirth. Triggers such as hypoxia-ischaemia result …

Hypothermia combined with extracellular vesicles from clonally expanded immortalized mesenchymal stromal cells improves neurodevelopmental impairment in …

N Labusek, P Ghari, Y Mouloud, C Köster… - Journal of …, 2023 - Springer
Background Neonatal encephalopathy following hypoxia–ischemia (HI) is a leading cause
of childhood death and morbidity. Hypothermia (HT), the only available but obligatory …

The association of placental pathology and neurodevelopmental outcomes in patients with neonatal encephalopathy

AC Stone, KC Strickland, DT Tanaka, JB Gilner… - Pediatric …, 2023 - nature.com
Background Studies conflict on how acute versus chronic placental pathology impacts
outcomes after neonatal encephalopathy from presumed hypoxic-ischemic encephalopathy …

Artificial intelligence outcome prediction in neonates with encephalopathy (AI-OPiNE)

CO Lew, E Calabrese, JV Chen, F Tang… - Radiology: Artificial …, 2024 - pubs.rsna.org
Purpose To develop a deep learning algorithm to predict 2-year neurodevelopmental
outcomes in neonates with hypoxic-ischemic encephalopathy using MRI and basic clinical …

Impact of hypoxia-ischemia on neurogenesis and structural and functional outcomes in a mild–moderate neonatal hypoxia-ischemia brain injury model

A Ehlting, M Zweyer, E Maes, Y Schleehuber, H Doshi… - Life, 2022 - mdpi.com
Hypoxic-ischemic encephalopathy (HIE) is a common type of brain injury caused by a lack of
oxygen and blood flow to the brain during the perinatal period. The incidence of HIE is …

Hammersmith Infant Neurological Examination in infants born at term: Predicting outcomes other than cerebral palsy

DM Romeo, FM Cowan, L Haataja… - … Medicine & Child …, 2022 - Wiley Online Library
Aim We explored the ability of the Hammersmith Infant Neurological Examination (HINE) to
identify cognitive performance delay at 2 years in a large cohort of infants born at term …

The financial burden experienced by families during NICU hospitalization and after discharge: A single center, survey-based study

CV Lambiase, G Mansi, S Salomè, ML Conelli… - European Journal of …, 2024 - Springer
To investigate a broad array of costs and perceived financial burden (FB) faced by families
of NICU graduates both during hospitalization and after discharge. Cross-sectional survey …

Long-term outcomes after neonatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia: a longitudinal, prospective, multicenter case-control study …

E Cainelli, L Vedovelli, E Mastretta, D Gregori… - Children, 2021 - mdpi.com
Background. Data on long-term outcomes in the era before therapeutic hypothermia (TH)
showed a higher incidence of cognitive problems. Since the introduction of TH, data on its …

Subcortical brain volumes in neonatal hypoxic–ischemic encephalopathy

LMN Kebaya, B Kapoor, PC Mayorga, P Meyerink… - Pediatric …, 2023 - nature.com
Background Despite treatment with therapeutic hypothermia, hypoxic–ischemic
encephalopathy (HIE) is associated with adverse developmental outcomes, suggesting the …