Pharmacological mechanism of ketamine in suicidal behavior based on animal models of aggressiveness and impulsivity: a narrative review

TML Nguyen, F Jollant, L Tritschler, R Colle… - Pharmaceuticals, 2023 - mdpi.com
Around 700,000 people die from suicide each year in the world. Approximately 90% of
suicides have a history of mental illness, and more than two-thirds occur during a major …

Prevention of suicidal behavior with lithium treatment in patients with recurrent mood disorders

L Tondo, RJ Baldessarini - International journal of bipolar disorders, 2024 - Springer
Suicidal behavior is more prevalent in bipolar disorders than in other psychiatric illnesses. In
the last thirty years evidence has emerged to indicate that long-term treatment of bipolar …

Associations among the workplace violence, burnout, depressive symptoms, suicidality, and turnover intention in training physicians: a network analysis of nationwide …

JY Yun, SJ Myung, KS Kim - Scientific reports, 2023 - nature.com
Depression and anxiety are the most common mental disorders among physicians, who
have a greater risk of suicide than those in other professional occupations. Relationships …

New Advances in the Pharmacology and Toxicology of Lithium: A Neurobiologically Oriented Overview

A Bortolozzi, G Fico, M Berk, M Solmi, M Fornaro… - Pharmacological …, 2024 - ASPET
Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …

[HTML][HTML] Association between the mood stabilizing treatment of bipolar disorder and risk of suicide attempts: A self-controlled case series study

VWS Ng, MTY Leung, EW Chan, EHM Lee, JF Hayes… - Psychiatry …, 2023 - Elsevier
Bipolar disorder (BPD) is associated with high rates of suicide attempts but the anti-suicidal
effect of mood stabilizing agents remains unclear. This study aimed to examine the …

Real-world evidence from a retrospective study on suicide during depression: clinical characteristics, treatment patterns and disease burden

H Wang, N Lyu, J Huang, B Fu, L Shang, F Yang… - BMC psychiatry, 2024 - Springer
Background Suicide stands as both a primary symptom and the direst outcome of major
depressive disorder (MDD). The scarcity of effective treatment strategies makes managing …

A systematic review of the role of clozapine for severe borderline personality disorder

J Han, S Allison, JCL Looi, SKW Chan… - …, 2023 - Springer
Rationale Clozapine is a unique medication with a potential role in the treatment of severe
borderline personality disorder (BPD). Objectives The review examines the effectiveness of …

Mortality risk and mood stabilizers in bipolar disorder: a propensity-score-weighted population-based cohort study in 2002–2018

JKN Chan, CSM Wong, CZ Fang, SC Hung… - Epidemiology and …, 2024 - cambridge.org
AimsAccumulating studies have assessed mortality risk associated with mood-stabilizers,
the mainstay treatment for bipolar disorder (BD). However, existing data were mostly …

The risk of suicidal intention in severe mental illness: An ecological perspective

Y Lin, Q Wei, S Luo, X Ye, F Zheng… - Psychology and …, 2023 - Wiley Online Library
Objective Guided by the ecosystem theory model framework, we aimed to explore the
influence of three ecological dimensions (social, family and psychological factors) on …

Genetic signatures of suicide attempt behavior: insights and applications

A Drago - Expert review of proteomics, 2024 - Taylor & Francis
Introduction Every year about 800,000 complete suicide events occur. The identification of
biologic markers to identify subjects at risk would be helpful in targeting specific support …