Acute chemical emergencies

SN Kales, DC Christiani - New England Journal of Medicine, 2004 - Mass Medical Soc
Acute chemical emergencies can occur as a result of an industrial accident, occupational
exposure, a natural disaster, or an act of terrorism. This article reviews empirical principles …

Historical perspective on effects and treatment of sulfur mustard injuries

JS Graham, BA Schoneboom - Chemico-biological interactions, 2013 - Elsevier
Abstract Sulfur mustard (2, 2′-dichlorodiethyl sulfide; SM) is a potent vesicating chemical
warfare agent that poses a continuing threat to both military and civilian populations …

Ocular injuries following sulfur mustard exposure—pathological mechanism and potential therapy

T Kadar, S Dachir, L Cohen, R Sahar, E Fishbine… - Toxicology, 2009 - Elsevier
Sulfur mustard (SM) is a potent vesicant, known for its ability to cause incapacitation and
prolonged injuries to the eyes, skin and respiratory system. The toxic ocular events following …

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide–induced skin injury in SKH-1 hairless mice

N Tewari-Singh, S Rana, M Gu, A Pal… - Toxicological …, 2009 - academic.oup.com
Sulfur mustard (HD) is an alkylating and cytotoxic chemical warfare agent, which inflicts
severe skin toxicity and an inflammatory response. Effective medical countermeasures …

Differential toxicity of sulfur mustard administered through percutaneous, subcutaneous, and oral routes

R Vijayaraghavan, A Kulkarni, SC Pant, P Kumar… - Toxicology and applied …, 2005 - Elsevier
Sulfur mustard (SM), chemically 2, 2′-dichloro diethyl sulphide, is an incapacitating and
extremely toxic chemical warfare agent. It causes serious blisters on contact with human …

Corneal toxicity induced by vesicating agents and effective treatment options

DG Goswami, N Tewari‐Singh… - Annals of the New York …, 2016 - Wiley Online Library
The vesicating agents sulfur mustard (SM) and lewisite (LEW) are potent chemical warfare
agents that primarily cause damage to the ocular, skin, and respiratory systems. However …

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl …

AT Black, LB Joseph, RP Casillas, DE Heck… - Toxicology and applied …, 2010 - Elsevier
Dermal exposure to sulfur mustard causes inflammation and tissue injury. This is associated
with changes in expression of antioxidants and eicosanoids which contribute to oxidative …

A review on symptoms, treatments protocols, and proteomic profile in sulfur mustard‐exposed victims

Y Panahi, AH Abdolghaffari… - Journal of cellular …, 2018 - Wiley Online Library
Sulfur mustard (SM) as an alkylating and vesicating agent was used for 100 years as a
chemical weapon. SM as bi‐functional mustard can attacks and alkylates lots of …

Amelioration of sulfur mustard skin injury following a topical treatment with a mixture of a steroid and a NSAID

S Dachir, E Fishbeine, Y Meshulam… - Journal of Applied …, 2004 - Wiley Online Library
The ability to ameliorate sulfur mustard (HD)‐induced oedema by treatment with anti‐
inflammatory drugs was reported previously after screening four steroids and four non …

Inhalation exposure to sulfur mustard in the guinea pig model: clinical, biochemical and histopathological characterization of respiratory injuries

N Allon, A Amir, E Manisterski, I Rabinovitz… - Toxicology and applied …, 2009 - Elsevier
Guinea pigs (GP) were exposed (head only) in individual plethysmographs to various
concentrations of sulfur mustard vapor, determined online, using FTIR attached to flow …