Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Selenium (Se) is an essential micronutrient of organism and has important function. It
participates in the functions of selenoprotein in several manners. In recent years, Se has …

The high number of new cancer incidences and the associated mortality continue to be
alarming, leading to the search for new therapies that would be more effective and less …

Ebselen is the leader of selenorganic compounds, and starting from its identification as
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …

The isoenzyme of human glutathione transferase P1-1 (hGSTP1-1) is involved in multi-drug
resistance (MDR) mechanisms in numerous cancer cell lines. In the present study, the …

This review summarizes advancement in the field of pyridyl-based organochalcogen ligands
in terms of their coordination behavior and biological applications. Pyridylchalcogen …

Cancer is a serious problem affecting the health of all human societies. Chemotherapy
refers to the use of drugs to kill cancer or the origin of cancer. In the past three decades …

Selenium (Se) is a required micronutrient with numerous health implications for all life forms.
Organic Se species are considered nutritionally beneficial since they are highly bioavailable …

Pancreatic ductal adenocarcinoma (PDA) cells reprogram both mitochondrial and lysosomal
functions to support growth. At the same time, this causes significant dishomeostasis of free …

Chagas disease is one of the most prevalent tropical neglected diseases and causes high
mortality and morbidity in endemic countries. Current treatments for this disease, nifurtimox …