Recent evidence suggests that the traditional syndromes known as renal osteodystrophy,
secondary hyperparathyroidism, and vitamin D deficiency are related to mortality in persons …

Vascular calcification is an active, cell‐mediated process that can involve either the intima or
media of the blood vessels. The current methods used to clinically measure vascular …

OBJECTIVE: Phosphorus-containing additives are increasingly being added to food
products. We sought to determine the potential impact of these additives. We focused on …

Background and objectives: Recent studies show high prevalence of suboptimal 25-
hydroxyvitamin D levels in chronic kidney disease patients. This study sought to test the …

Mineralized bone forms when collagen-containing osteoid accrues mineral crystals. This is
initiated rapidly (primary mineralization), and continues slowly (secondary mineralization) …

Vascular calcification is one of the mechanisms mediating the higher mortality risk
associated with the hyperphosphatemia of chronic kidney disease. Though common, and …

Vascular calcification is a strong prognostic marker of mortality in hemodialysis patients and
has been associated with bone metabolism disorders in this population. In earlier stages of …

We conducted a systematic search across medical databases, including PubMed, Web of
Science, EMBASE, and Cochrane Library, up to March 2023. A total of 1944 subjects or …

Background: Patients on hemodialysis (HD) frequently experience cardiovascular events
associated with vascular calcification. We investigated the involvement of osteoprotegerin …

The prevailing paradigm of mineral metabolism in chronic kidney disease (CKD) is based on
two principles. First, as the tradeoff hypothesis suggests, phosphate retention leads to …