We performed this systematic review to assess the analgesic efficacy of perioperative
pregabalin. Subgroup analyses and meta-regression were performed to assess the impact …

2. Methods We prospectively registered our systematic review with the International
Prospective Register of Systematic Reviews (PROSPERO)(CRD42012002078). We then …

Background: Gabapentinoid drugs, which include gabapentin and pregabalin, play an
established role in the management of neuropathic pain. However, whether preoperative …

The efficacy of pregabalin in acute postsurgical pain has been demonstrated in numerous
studies; however, the analgesic efficacy and adverse effects of using pregabalin in various …

Pregabalin has demonstrated anti-hyperalgesic properties and was introduced into acute
pain treatment in 2001. Our aim was to evaluate the beneficial and harmful effects of …

Background Pregabalin (PGB) and gabapentin (GBP) are current and emerging drugs in the
field of pre-emptive preoperative analgesia. However, the role of PGB or GBP in acute …

Purpose With lumbar laminectomy increasingly being performed on an outpatient basis,
optimal pain management is critical to avoid post-operative delay in discharge and …

Intervertebral disc degeneration (IDD) and associated conditions are an important problem
in modern medicine. The onset of IDD may be in childhood and adolescence in patients with …

Background: We performed a systematic review and meta-analysis of randomized controlled
trials (RCTs) to evaluate the efficacy and safety of pregabalin for pain management following …

IMPORTANCE Patients undergoing spine surgery often experience severe pain. The
optimal dosage of pregabalin and gabapentin for pain control and safety in these patients …