[HTML][HTML] Anti-inflammatory, antioxidant, and neuroprotective effects of polyphenols—polyphenols as an element of diet therapy in depressive disorders

A Winiarska-Mieczan, M Kwiecień… - International Journal of …, 2023 - mdpi.com
Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

[HTML][HTML] Neuroprotective potentials of flavonoids: Experimental studies and mechanisms of action

P Bellavite - Antioxidants, 2023 - mdpi.com
Neurological and neurodegenerative diseases, particularly those related to aging, are on
the rise, but drug therapies are rarely curative. Functional disorders and the organic …

[HTML][HTML] Quercetin antagonizes the sedative effects of linalool, possibly through the GABAergic interaction pathway

MH Bappi, AAS Prottay, H Kamli, FA Sonia, MN Mia… - Molecules, 2023 - mdpi.com
Sedatives promote calmness or sleepiness during surgery or severely stressful events. In
addition, depression is a mental health issue that negatively affects emotional well-being. A …

Quercetin increases the antidepressant‐like effects of sclareol and antagonizes diazepam in thiopental sodium‐induced sleeping mice: a possible GABAergic …

MH Bappi, MN Mia, SA Ansari, IA Ansari… - Phytotherapy …, 2024 - Wiley Online Library
Quercetin is the most common polyphenolic flavonoid present in fruits and vegetables
demonstrating versatile health‐promoting effects. This study aimed to examine the effects of …

[HTML][HTML] The therapeutic effects of saikosaponins on depression through the modulation of neuroplasticity: From molecular mechanisms to potential clinical …

S Chen, K Wang, H Wang, Y Gao, K Nie, X Jiang… - Pharmacological …, 2024 - Elsevier
Depression is a major global health issue that urgently requires innovative and precise
treatment options. In this context, saikosaponin has emerged as a promising candidate …

[HTML][HTML] Flavonols in action: Targeting oxidative stress and neuroinflammation in major depressive disorder

M Jazvinšćak Jembrek, N Oršolić, D Karlović… - International journal of …, 2023 - mdpi.com
Major depressive disorder is one of the most common mental illnesses that highly impairs
quality of life. Pharmacological interventions are mainly focused on altered monoamine …

[HTML][HTML] Systems biology approaches to identify potential targets and inhibitors of the intestinal microbiota to treat depression

F Teng, Z Lu, F Gao, J Liang, J Li, X Tian, X Wang… - Scientific reports, 2023 - nature.com
Depression is a common mental disease, with some patients exhibiting ideas and behaviors
such as self-harm and suicide. The drugs currently used to treat depression have not …

[HTML][HTML] Antidepressant-like effects of representative types of food and their possible mechanisms

J Piao, Y Wang, T Zhang, J Zhao, Q Lv, M Ruan, Q Yu… - Molecules, 2023 - mdpi.com
Depression is a mental disorder characterized by low mood, lack of motivation, negative
cognitive outlook, and sleep problems. Suicide may occur in severe cases, although suicidal …

[HTML][HTML] Biology of cyclooxygenase-2: An application in depression therapeutics

Y He, Y Han, X Liao, M Zou, Y Wang - Frontiers in Psychiatry, 2022 - frontiersin.org
Depressive Disorder is a common mood disorder or affective disorder that is dominated by
depressed mood. It is characterized by a high incidence and recurrence. The onset of …

[HTML][HTML] Impact of Baizhu, Daqingye, and Hehuanhua extracts on the human gut microbiome

JMS Lemons, AB Narrowe, LS Liu, J Firrman… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction In traditional Chinese medicine, the rhizome of Atractylodes macrocephala
(Baizhu), the leaves of Isatis indigotica (Daqingye), and the flowers of Albizia julibrissin …